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脑电非线性分析监测在异丙酚靶控输注中的应用

Application of EEG nonlinear analysis in anaesthesia with target controlled infusion of propofol
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摘要 目的:本研究采用脑电非线性分析监测技术,研究异丙酚靶控麻醉对不同脑区的作用,并探讨其临床意义。方法:选择40例择期行腹部手术的患者,随机分为异丙酚3μg/mL靶控输注组(A组)、异丙酚4μg/mL靶控输注组(B组),每组20例。麻醉方法采用全凭静脉异丙酚靶控麻醉,监测患者清醒时、诱导、术中、苏醒、出室时的脑电非线性参数—近似熵(ApEn)、关联维数(D2)和复杂度(Cx),以及血压(BP)、心率(HR)、脉搏血氧饱和度(SpO2)变化。结果:异丙酚镇静下患者各个脑区的非线性参数值均下降,差异有统计学意义(P<0.05);组内患者,术中与清醒时、苏醒相比较,ApEn、D2和Cx下降差异有统计学意义(P<0.05);A组与B组之间,同一阶段ApEn、D2、Cx下降幅度差异无统计学意义(P>0.05);异丙酚达到靶控浓度过程中脑区从额叶和顶叶区向颞叶和枕叶逐渐被抑制,停药以后脑区又从颞叶和枕叶区向额叶和顶叶逐渐恢复兴奋。结论:在麻醉的不同阶段、不同脑区监测到的脑电非线性参数不同;异丙酚3μg/mL靶控输注与异丙酚4μg/mL靶控输注,两组浓度对脑区的抑制在非线性监测下差异无统计学意义。 AIM: To study the effects of anaesthesia on different encephalic regions with target controlled infusion of propofol using EEG nonlinear analysis method and to investigate its clinical significance.METHODS:40 patients undergoing selected abdomen operations were randomly divided into propofol group A(3 μg/mL) and group B(4 μg/mL),n=20.EEG nonlinear parameters such as approximate entropy(ApEn),association dimension(D2),complexity(Cx) were recorded using total intravenous anesthesia,and the changes of blood pr...
出处 《中国临床药理学与治疗学》 CAS CSCD 2008年第11期1263-1267,共5页 Chinese Journal of Clinical Pharmacology and Therapeutics
基金 国家自然科学基金项目(30571792)
关键词 非线性脑电图 近似熵 关联维数 复杂度 异丙酚 nonlinear electroencephalogram approximate entropy correlation dimensionality complexity propofol
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  • 1杨治良,叶阁蔚,王新发.汉字内隐记忆的实验研究(Ⅰ)──内隐记忆存在的条件[J].心理学报,1994,26(1):1-7. 被引量:35
  • 2张作生,彭虎,公佩祥.几种不同认知事件下40Hz脑电事件相关电位的分维特性比较[J].中国科学技术大学学报,1997,27(1):39-43. 被引量:2
  • 3Stapleton CL, Andrade J. An investigation of learning during propofol sedation and anesthesia using the process dissociation procedure. Anesthesiology, 2000, 93:1418 被引量:1
  • 4Stapleton CL, Andrade J. An investigation of learning during propofol sedation and anesthesia using the process dissociation procedure. Anesthesiology, 2000, 93 : 1418. 被引量:1
  • 5Veselis RA, Reinsel RA, Feshchenko VA et al. A neuroanatomical construct for the amnesic effects of propofol. Anesthesiology, 2002, 97(2):329. 被引量:1
  • 6De Roode A,Van Gerven JMA,Schoemaker RC et al. A tzomparison of the effects of propofol and midazolarn on memory during two levels of sedation by using Target Controlled Infusioru Anesth Analg, 2000, 91:1056. 被引量:1
  • 7Rich JB, Yaster M, Brandt J. Anterograde and retrograde memory in children anesthetized with propofol. J Clin Exp Neuropsychol, 1999,21(4) :535. 被引量:1
  • 8Munte S, Munte TF, Mitzzlaff B etal. Postoperative reading speed does not indicate implicit memory in elderly cardiac patients after propofol and remifentanil anaesthesia. Acta Anaesthesiol Scand, 2001, 45:750. 被引量:1
  • 9Kerssens C, Klein J, van der Woerd A et al. Auditory information processing during adequate propofol anesthesia monitored by electroencephalogram Bispectral index. Anesth Analg, 2001,92 : 1210. 被引量:1
  • 10Pincus SM. Greater signal regularity may indicate increased system isolation. Math Biosci, 1994, 122:161. 被引量:1

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