摘要
目的探讨肺癌脑转移瘤对合并使用地塞米松(Dexamethasone,DXT)及甘露醇(Mannitol,MT)的反应性与伽玛刀治疗效果的关系。方法回顾性分析37例肺癌脑转移瘤病人的伽玛刀治疗情况。根据对DXT+MT治疗的反应性,将病人分为两组,比较两组病人的伽玛刀治疗效果。结果24例(65%)对DXT+MT治疗反应良好。伽玛刀治疗后,平均随访6.7个月(3~13个月),肿瘤生长得到有效控制32例(87%),其中23例对DXT+MT治疗反应良好。统计分析显示:肿瘤生长控制率在反应良好组中明显较高。结论在肺癌脑转移瘤伽玛刀治疗适应证选择和预后判定中,对DXT+MT治疗的反应性可视为一个粗略标准。
Objective To explore the relationship between the reactivity to dexamethasone(DXT) combined with mannitol(MT) and the efficacy of Gamma knife radiosurgery for metastases from lung cancer.Methods Thirty-seven patients harbored metastases from lung cancer treated with Gamma knife were retrospectively reviewed.Based on the reactivity to DXT+MT, these patients were divided into two groups.The Gamma knife radiosurgical outcome was compared between the two groups.Results Of 37 the patients, 24(65%) showed good re...
出处
《中国微侵袭神经外科杂志》
CAS
2008年第12期540-541,共2页
Chinese Journal of Minimally Invasive Neurosurgery