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经肝动脉外周血干细胞移植治疗失代偿期肝硬化11例 被引量:3

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摘要 目的探讨经肝动脉外周血干细胞移植(APBSCT)治疗失代偿期肝硬化的疗效。方法回顾分析2006年10月~2008年2月我院11例APBSCT患者的临床资料及生化指标。结果11例患者移植后2、4、8周及12周,有9例(81.82%)TBIL逐渐下降,8例(72.73%)ALB逐渐升高,10例(90.91%)PTA逐渐升高;移植后12周内,腹水减轻7例(63.64%),食欲改善8例(72.73%),体力好转7例(63.64%),腹胀减轻7例(63.64%)。除1例出现轻微骨痛以外,未发现其它明显不良反应及并发症。结论APBSCT是安全可行的,能够在一定程度上改善失代偿期肝硬化患者的临床症状及肝功能。
出处 《福建医药杂志》 CAS 2008年第6期29-31,共3页 Fujian Medical Journal
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  • 1Pittenger MF Mackay AM,Jaiswal SC,et al.Multitineage potential of adult human mesenchymal stem cells.Science,1999,284(5411):143-147. 被引量:1
  • 2Y Jiang,B.N Jahagirdar,R.L Reinhardt,et al.Pluripotency of mesenchymal stem cells derived from adult marrow.Nature,2002,418(6893):41-49. 被引量:1
  • 3Sautin YY,Jorgensen M,Petersen BE,et al.Hepatic oval(stem)cell expression of endothelial differentiation gene receptors for lysophosphatidic acid in mouse chronic liver injury.J Hematother Stem Cell Res,2002,11(4):643-649. 被引量:1
  • 4Ohgushi H,Caplan Al.Stem cell technology and biocramics:from cell to gene engineering.J Biomed Mater Res,1999,48(6):913-927. 被引量:1
  • 5Conget PA,Minguell JJ.Phenotypical and functional properties of human bone marrow mesenchynml progenitor cells.J Cell Physiol,1999,181(1):67-73. 被引量:1
  • 6OH SH,Miyazaki M,Kouchi H,et al.Hepatocyte growth factor induces differentiation of adult rat bone marrow cells into a hepatocyte lineage in vitro.Bioch Bioph Res commu,2000,279(2):500-504. 被引量:1
  • 7RE Schwartz,M Reyes,L Koodie,et al.Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cells.J Clin Invest,2002,109(10):1291-1302. 被引量:1
  • 8Jung J,Zheng MH,Goldfarb M,et al.Initiation of mammalian liver development from endoderm by fibroblast growth factors,Science,1999,248(18):1998-2003. 被引量:1
  • 9Wollert KC, Meyer GP, Lotz J, Ringes-Lichtenberg S, Lippolt P, Breidenbach C, Fichtner S, Korte T, Homig B, Messinger D,Arseniev L, Hertenstein B, Ganser A, Drexler H. Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomized controlled clinical trial. Lancet 2004;364:141-148 被引量:1
  • 10Yao P, Zhan Y, Xu W, Li C, Yue P, Xu C, Hu D, Qu CK, Yang X. Hepatocyte growth factor-induced proliferation of hepatic stem-like cells depends on activation of NF-kappaB.J Hepatol 2004;40:391-398 被引量:1

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