摘要
目的:探讨盐酸消旋山莨菪碱预防乳腺癌术后皮瓣坏死的作用。方法:对312例乳腺癌改良根治术后患者随机分为两组,A组为实验组采用消旋山莨菪碱20mg/kg+0.9%氯化钠注射液50m l微量每日泵静推,B组采用常规方式治疗,比较两组切口皮瓣愈合情况。结果:A组176例中皮瓣坏死22例(12.5%)B组136例皮瓣坏死36例(26.4%),横行切口和纵行手术切口均显示用盐酸消旋山莨菪碱可降低皮瓣坏死率。结论:手术是发生皮瓣坏死的危险因素,纵切口发生皮瓣坏死的风险更大,应用盐酸消旋山莨菪碱可使乳腺癌术后皮瓣坏死率降低。
Objective:To approach the effect of Racanisodamine in the preservation of flap necrosis after breast surgery.Methods: To divide randomly 312 patients with modified radical mastectomy into two goups.The patients in group A were administrated racanisodamine 20mg/kg and 0.9% sodium chloride through micro pump every day as experimental group,and those in group B were treated with common mathad as control group.Both two groups included patients operated with transverse or longitudinal incision.Compared the incid...
出处
《现代肿瘤医学》
CAS
2008年第11期1938-1939,共2页
Journal of Modern Oncology
关键词
乳腺肿瘤
山莨菪碱
皮瓣坏死
术后并发症
breast tumor
racanisodamine
flap necrosis
postoperative complications
