摘要
目的探讨脑脉泰胶囊治疗颈内动脉系统动脉硬化性脑梗死(ATCI)患者的疗效及对脑循环动力学的影响。方法对88例ATCI患者进行了脑循环动力学观察。采用随机、双盲和平行对照的方法,将88例患者分为治疗组和对照组,对照组患者接受脑梗死的常规治疗,治疗组患者在常规治疗基础上加用脑脉泰胶囊治疗。治疗组患者用脑脉泰胶囊治疗前、治疗28 d后进行脑神经功能缺损评分,同时测定脑循环动力学参数(CVD I),并对对照组治疗前、后测得的结果进行比较。结果(1)治疗后两组神经功能缺损总分比较差异有统计学意义(P<0.05)。(2)两组疗效比较差异有统计学意义(P<0.05)。(3)治疗组患者病灶一侧CVD I中,脑血流量(Q)及血流速度治疗后较治疗前差异有统计学意义(P<0.05),较对照组差异亦有统计学意义(P<0.05)。治疗组治疗后外周血管阻力较治疗前差异有统计学意义(P<0.05)。结论脑脉泰胶囊治疗ATCI患者疗效好,能明显改善脑血流灌注,降低脑循环阻力,减少神经功能缺损,从而达到治疗脑梗死的目的,作为脑梗死的治疗药物安全有效。
Objective To observe the clinical efficacy of Naomaitai capsules on cerebral hemodynamics in patients with atherothrombotic cerebral infarction(ATCI) of the internal carotid artery(ICA) system.Methods Cerebral circulation dynamical observation was carried out on data of 88 ATCI patients.All patients were divided into 2 groups by randomized,double-blind and parallel-control methods.Both were given the same basic routine treatment,but treatment group given additional Naomaitai capsules.Cranial neurologic impa...
出处
《中国全科医学》
CAS
CSCD
2008年第24期2270-2272,共3页
Chinese General Practice
关键词
脑脉泰胶囊
脑梗死
脑循环动力学参数
疗效
Naomaitai capsules
Cerebral infarction
Cerebral circulation kinetic parameter
Therapeutic effect
