摘要
目的:利用组织多普勒成像(Tissue Doppler Imaging,TDI)技术,评价糖化血红蛋白(Glycosylated Hemoglobin,GHb)异常的2型糖尿病(Type 2 Diabetes Mellitus,DM2)患者的心脏左室舒张功能。方法:应用TDI技术观测二尖瓣环心肌舒张早期速度(Em)和舒张晚期速度(Am),应用脉冲多普勒成像(Pulse Doppler Imaging,PDI)技术测量二尖瓣口舒张早期最大血流速率(E)和舒张晚期最大血流速率(A),并计算Em/Am、E/A。结果:与正常对照组(NOR组)相比,DM2组的Em/Am、E/A显著减低,有统计学意义;而A稍高及Am稍低、Em稍低、E稍低,这些参数均无统计学意义。40例GHb异常的DM2组,以Em/Am<1及E/A<1等提示舒张功能减退,与NOR组相比,DM2组有统计学意义。结论:超声检查,尤其是TDI技术,能较好的评价GHb异常DM2的心脏舒张功能。
Objective Using TDI to evaluate left ventricular diastolic function of abnormal glycosylated hemoglobin (GHb) type 2 diabetes mellitus (DM2). Methods Using TDI to observe the early diastolic velocity (Em) and the advanced diastolic velocity (Am) at mitral central myocardial, and using PDI to measure the most diastolic blood flow velocity (E) early and the most diastolic blood flow velocity (A) advanced at mitral, and calculated Em/Am, E/A. Results Compared with the normal group, Em/Am and E/A in DM2 group had reduced significantly. A made higher slightly, Em、Am and E made lower slightly, all these parameters were not statistically significant. If Em/Am < 1 and E/A < 1 were considered parameters as diastolic dysfunction,compard with normal group, DM2 group with abnormal GHb was statistical significance. Conclusion Ultrasound technology, in particular TDI, is able to better evaluate left ventricular diastolic function of abnormal GHb DM2.
出处
《深圳中西医结合杂志》
2008年第4期232-235,共4页
Shenzhen Journal of Integrated Traditional Chinese and Western Medicine
基金
深圳市科技和信息局科研课题(200702101)
关键词
组织多普勒成像
2型糖尿病
糖化血红蛋白
左心舒张功能
Tissue doppler imaging
2 type diabetes
Glycosylated hemoglobin
Left ventricular diastolic function
