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γ干扰素与小柴胡汤联合抗肝纤维化的研究 被引量:2

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摘要 目的:寻找抗肝纤维化的有效方法。方法:用γ干扰素(IFN-γ)和小柴胡汤联合治疗慢性乙型肝炎患者60例,并与单纯应用IFN-γ治疗慢性乙型肝炎50例比较,观察治疗前后患者透明质酸(HA)、Ⅳ型胶原(Ⅳ-C)、层粘蛋白(LN)、肝功能等指标变化。结果:IFN-γ联合小柴胡汤组患者血清肝圩堆化指标、ALT、TBil下降明显,A/G比值上升显著,与治疗前、单用IFN-γ组比较有显著性差异。结论:IFN-γ和小柴胡汤联合应用可有效改善患者肝功能,减轻和抑制肝纤维化的发生。
出处 《中西医结合肝病杂志》 CAS 2001年第S1期95-,共1页 Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases
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  • 1[1]Ono M, Miyamura M, Kyotani S, et al. Effect of Shosaikoto extract on HGF and TGF-beta levels of intraorgans in liver-injured rats after partial hepatectomy. J Pharm Pharmacol. 2000, 52 (1): 111 被引量:1
  • 2[2]Ono M, Miyamura M, Kyotani S, et al. Effects of Shosaikoto extract on liver fibrosis in relation to the changes in hydroxyproline and retinoid levels of the liver in rats. J Pharm Pharmacol. 1999, 51 (9): 1079 被引量:1
  • 3[3]Miyamura M, Ono M, Kyotani S, et al. Effects of Shosaikoto extract on fibrosis and regeneration of the liver in rats. J Pharm Pharmacol. 1998, 50 (1): 97 被引量:1
  • 4[4]llattori Y, Kasai K, Sekiguchi Y, et al. The herbal medicine Shosaikoto induces nitric oxide synthese in rat hepatocytes. Life Sci, 1995, 56 (7): PL143 被引量:1
  • 5[5]Sakaguchi S, Furusawa S, Yokota K, et al. Depressive effect of a traditional Chinese medicine (Shosaikoto)on endotoxin induced nitric oxide formation in activated murine macrophage J774A. 1 cells. Biol PharmBull, 1995, 18 (4): 621 被引量:1
  • 6[6]Shimizu I, Ma YR, Mizobuchi Y, et al. Effects of Shosaikoto, a Japanese herbal medicine, on hepatic fibrosis in rats. Hepatology. 1999, 29 (1): 149 被引量:1
  • 7[7]Kayano K,Sakaida I,Uchida K,et al. Inhibitory effects of the hcrbal medicine Shosaikoto (TJ 9)on cell proliferation and procollagen gene expressions in cultured rat hepatic stellate cells. J Hepatol. 1998, 29(4): 642 被引量:1
  • 8[8]Yamashiki M, Kosaka Y, Nishimura A, et al. Efficacy of a herbal medicine“Shosaikoto”on the improvement of impaired cytokine production of peripheral blood mononuclear cells in patients with chronic viral hepatitis. J Clin Lab Immunol. 1992, 37 (3): 111 被引量:1
  • 9[9]Fujiwara K, Mochida S, Nagoshi S, et al. Regulation of hepatic macrophage function by oral administration of Xiaochaihutang (Shosaikoto, TJ 9) in rats. J Ethnopharmacol. 1995, 46 (2): 107 被引量:1
  • 10[10]Yamashiki M, Nishimura A, Suzuki LL, et al. Effe cts of the Japanese herbal medicine “Shosaikoto” (TJ9) on in vitro interleukin 10 production by peripheral blood mononuclear cells of patients with chronic hepatitis C. Hepatology. 1997, 25 (6): 1390 被引量:1

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