摘要
目的 探讨不同手术前后肺癌患者的NK细胞和T细胞亚群的变化情况。方法 选择不同分期的肺癌患者 ,通过不同手术治疗 ,于手术前后 2周内采外周血 ,采用胞浆乳酸 (脱氢酶 )释放法测NK细胞活性 ,采用APAAP法测T细胞亚群 ,所获数据经方差分析 ,求P值用t检验。结果 肺癌患者的免疫功能与肿瘤大小呈负相关 ,提示这种免疫功能有明显的改善。结论 不论哪期肺癌患者只要机体情况许可 ,均应做肿瘤切除术。只要原发瘤存在其免疫功能就日渐下降 ,影响存活期。
Objective To study the changes of preoperative and postoperative lung cancer from NK cells and T cells subgroup.Methods Take peripheral-blood of patients in two weeks before and after operation by selecting different premiun lung cancer and using different operation treatments.Examine NK cells activity by taking cytoplassmic lacticaced release method.Examine T cells subgroup by taking APAAP method,analyse data obtained.Rusults The immunologic function of patients with lung cancer and the size of tumor appeared negative correlation,the immunologic inhibition was tumor protogonccyte.The immunologic function was improved after cutting the tumor.Conclusion If organism permits, the tumor should be cut.If the premary tumor exists,the immunologyic function will fall.It can influence survival time.
出处
《菏泽医学专科学校学报》
2002年第2期74-76,共3页
Journal of Heze Medical College
