摘要
目的观察六味地黄汤对慢性阴虚血瘀证模型大鼠血液流变性的影响。方法以注射氢化可的松及盐酸肾上腺素造成大鼠慢性阴虚血瘀模型,灌胃给予药物处理,于末次给药1.5h后颈动脉插管放血;分别测定全血黏度、血浆黏度、血沉、红细胞压积、血小板聚集率及粘附率。结果六味地黄汤13.50、6.75及3.78g生药/kg均能降低慢性阴虚血瘀证模型大鼠全血黏度、血浆黏度、红细胞压积、血沉、血小板聚集率及粘附率。结论六味地黄汤具有改善慢性阴虚血瘀证模型大鼠血液流变性的作用。
Objective To research the effects of Liuweidihuang Formula (LWDHF) on hemorrheology in rats with chronic yin asthenia and blood stasis.Methods The model rats with yin asthenia and blood stasis were established with administration hydrocortisone (10mg/kg, im.) for 14 days, treatment with LWDHF (ig.) since the 7th day. Epinephrine (0.5mg/kg, sc.) was injected on the 14th day and an hour before bloodletting. Viscosity of blood and plasma,erythrocyte sedimentation,volume of packed red cells, and the rates of pl...
出处
《中国血液流变学杂志》
CAS
2008年第1期14-16,共3页
Chinese Journal of Hemorheology
关键词
六味地黄汤
阴虚血瘀证
血液流变性
Liuweidihuang Formula
yin asthenia and blood stasis
hemorrheology
