摘要
目的探讨急性脑卒中患者血清红细胞生成素(EPO)水平改变及其临床意义。方法应用放射免疫法检测60例脑梗死(脑梗死组)、45例脑出血(脑出血组)和40例其他神经系统疾病患者(对照组)的血清EPO水平。用美国国立卫生研究院卒中量表(NIHSS)对急性脑卒中患者进行评分。结果脑梗死组和脑出血组血清EPO水平[(1.64±0.41)ng/ml,(1.59±0.54)ng/ml]显著高于对照组[(1.17±0.86)ng/ml](均P<0.05),脑梗死组及脑出血组的NIHSS评分[(10.42±3.75)分,(11.58±4.16)分]与血清EPO水平呈负相关(r=-0.482,r=-0.537,均P<0.05)。结论急性脑卒中患者的血清EPO水平明显升高,并且病情越重的患者血清EPO水平越低。
Objective To investigate the change and its clinical significance of serum erythropoietin(EPO) content in the patients with acute cerebral stroke.Methods The serum EPO content in 60 patients with acute cerebral infarction(ACI),45 patients with cerebral hemorrhage(CH) and 40 patients with other nervous system diseases(control group) were detected by radio-immunity means.The patients with acute cerebral stroke were evaluated by National Institute of Health Stroke Scale(NIHSS).Results The serum EPO content in ...
出处
《临床神经病学杂志》
CAS
北大核心
2008年第5期379-380,共2页
Journal of Clinical Neurology
关键词
红细胞生成素
急性脑卒中
脑梗死
脑出血
erythropoietin
acute cerebral stroke
cerebral infarction
cerebral hemorrhage
