摘要
目的:评价各种贲门失弛缓症治疗方法的有效性和安全性。方法:检索Medline数据库、Cochrane图书馆的随机对照试验和系统评价以及NGC(national guideline clearinghouse)网站相关临床指南,评价贲门失弛缓症的各种治疗方法,为临床实践提供最佳的循证医学证据。结果:共检索到18项结果,共评估了药物治疗、内镜下治疗和外科治疗贲门失弛缓症的疗效和安全性。结论:基于目前的临床证据,我们认为,药物治疗可作为一种暂时治疗方法;内镜下气囊扩张治疗可作为首选治疗方法;内镜下注射肉毒杆菌毒素治疗可作为那些不适合作明确治疗(气囊扩张或手术治疗)患者的一种辅助治疗。对于那些反复扩张或注射效果不佳患者,推荐外科治疗。
Objective:To review the efficacy and safety of various treatments on achalasia.Methods:Search of the systematic reviews and randomized controlled trials of achalasia were carried out through The Cochrane Library、Medline and NGC(national guideline clearinghouse)websites.Results:Eighteen outcomes were found which reviewed the efficacy and safety of drugs treatments、and injection BT treatment under endoscope、dilation therapy under endoscope and Surgical Treatment.Conclusion:Based on the present evidence,we con...
出处
《华西医学》
CAS
2008年第5期957-959,共3页
West China Medical Journal
