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血小板源性内皮生长因子在肝癌的表达及意义

Expression and Significance in Platelet-Derived-Epithelial Cell Growth Factor on Hepatocellular Carcinoma
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摘要 目的 探讨 PD- ECGF在肝癌诊断、鉴别诊断中的意义。 方法 应用 SP免疫组织化学方法观察 5例肝癌细胞的血小板源性内皮细胞生长因子 (PD- ECGF)表达情况及其在癌旁组织 (小结节性肝硬化、肝细胞增生等 )和正常肝细胞的不同表达 ,分析其与肝癌诊断的关系。 结果 肝癌细胞 PD- ECGF表达强阳性 ,癌旁增生的肝细胞 PD- ECGF弱阳性 ,正常肝细胞 PD- ECGF弱阳性或阴性。 PD- ECGF表达与组织学分型无关。 结论  PD-ECGF的表达情况可作为肝癌诊断、鉴别诊断的一种标志物。 Objective\ To study the platelet\|derived\|epithelial cell growth factor(PD\|ECGF) expression in hepatocellular carcinoma, cancer peripheral tissue, healthy hepatocyte and to investigate the significance of PD\|ECGF in the development of hepatocellular carcinoma.\ Methods\ 5 cases operative samples of hepatocellular carcinoma, peripheral tissue of cancer and healthy hepatocyte, were stained for PD\|ECGF by SP immunohistochemical methods.\ Results\ The PD\|ECGF expression of hepatocellular carcinoma were all...
出处 《福建医科大学学报》 2003年第S1期73-74,110,共3页 Journal of Fujian Medical University
关键词 肝细胞 肝肿瘤 血小板源生长因子 肿瘤标记 生物学 免疫组织化学 hepatocellular carcinoma platelet derived\|epithelial cell growth factor immunohistochemistry marker biology
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  • 1丛文铭,吴孟超,陈汉,张秀忠,董秀芬.DNA含量分析对复发性肝细胞癌克隆来源及其临床意义的初步研究[J].临床肝胆病杂志,1993,9(1):3-5. 被引量:26
  • 2丛文铭,吴孟超.小肝细胞癌的临床病理特点:附93例分析[J].中华肿瘤杂志,1993,15(5):372-374. 被引量:35
  • 3汪鸿志,江华,张志宏,韩树堂,徐肇敏.消化系统恶性肿瘤的临床早期诊断[J].中国实用内科杂志,1996,16(1):3-5. 被引量:7
  • 4Barrette P, Trarers M, Lngmani Y, Coombes RC. Transforming growth factors in human breast cancer: clinical corelates[J]. Br J Cancer,1990;61:612-617. 被引量:1
  • 5Schrieber AB, Winkler ME,Derynck R. Tran sforming growth factor-α: a more Potent angiogenic mediator than epidermal growth factor[J]. Solace, 1986 ; 232: 1250-1253. 被引量:1
  • 6Nishida M, Hino A, Mori K ,et al. Preparation of anti-human thymidine phosphory Lase monoclonal antibodies useful for detecting the enzyme levels in tumor tissuer[J]. Biol Pharm Bull, 1996; 19 :1407-1411. 被引量:1
  • 7Miyadera KJ, Sumizawa T, Haraguchi M ,et aL Role of thymidine phosphorylase activity in the angiogenic effect of platetderived endothelial cell growth factor/thymidine phosphorylase[J]. Cancer Res,1995 ; 55 :1687-1690. 被引量:1
  • 8Maeda K,Chung YS,Ogawa Y,et al. Thymidine phosphorylase/platelet-detived endothelial cell growth factor expression associated with hepatic metastasis in gastric carcinoma[J]. Br J Cancer,1996;73:884-888. 被引量:1
  • 9黄海珍 陈晓 董曲文.TSGF在肿瘤普查中的应用[J].实用预防医学,2002,14(1):98-98. 被引量:3
  • 10Kamat BR,Brown LF,Manseau EJ,etal.Expression of vascular permeability factor/vascular endothelial growth factor by humangranulosa and theca lutein cells.Role in corpus leteum development[J]..Am JPathol,1995;146:157~165 被引量:1

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