摘要
1966年4~5月在新疆巴楚县阿克沙克马拉勒地区发生5例以发热和出血为主要症状的病人,入院后经抢救治疗,3例死亡,2例痊愈出院。主要的症状和体征包括:起病急骤、寒战、发热、体温可达40℃以上。显著乏力、嗜睡、肢体疼痛、面颈部潮红、恶心、呕吐、继之出现皮肤及粘膜出血、鼻出血,可发展至消化道大量出血(呕血、便血)、血尿、低血压。早期即有蛋白尿、白细胞和血小板减少。4例患者在发病第2,4,5和9天从血液标本中分离到病毒。从2例尸检的肝、脾、肾和淋巴结标本中也分离到病毒,3例患者血清对本身分离的病毒中和试验阳性,2例双份血清的中和抗体有4倍以上增长。
Five patients with febrile and hemorrhage as the main symptoms were hospitalized in Aksakmaral area of Bachu County in the period of April-May, 1966. Three cases died and two cases convalesced after rescue and treatment. The main symptoms and physical signs were sudden onset of ill, chill, hyperthermia, acratia, lethargy, acrodynia, flash of face and neck, nosea and vomiting and followed by hemorrhage, which from hemorrhagic spot on skin and mucosa developed to severe bleeding of digestive tract and hematur...
出处
《地方病通报》
2004年第S1期1-5,共5页
Endemic Diseases Bulletin
关键词
急性发热
出血
病毒分离
中和抗体
巴楚
新疆
Acute febrile
Hemorrhage
Virus isolation
Neutralizing antibody
Bachu
Xinjiang