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Synthesis of New Bifunctional Bis(oxazolines) and Their Application in the Asymmetric Cyanosilylation of Aromatic Ketones

Synthesis of New Bifunctional Bis(oxazolines) and Their Application in the Asymmetric Cyanosilylation of Aromatic Ketones
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摘要   Catalytic asymmetric synthesis of tertiary cyanohydrins by the addition of cyanide to a wide range of ketones has important synthetic utility, since the resulting optically active cyanohydrins are important intermediates for the synthesis of a variety of valuable classes of chiral compounds. The application of oxazoline in asymmetric cyanosilylation has seldom reported in comparation with other reactions.[1] Recently, polymer-supported pyridine-bis(oxazoline) ytterbium complex was reported to catalyze cyanosilylation of benzaldehyde.……
出处 《有机化学》 SCIE CAS CSCD 北大核心 2004年第z1期3-,共1页 Chinese Journal of Organic Chemistry
基金 Project supported by the National Natural Science Foundation of China (Nos. 20372001, 20172001).
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  • 1[1]Aspinall, H. C.; Greeves, N.; Smith, P. M. Tetrahedron Lett. 1999, 43, 1763. 被引量:1
  • 2[2]Lundgren, S.; Lutsenko, S.; Jonsson, C.; Moberg, C. Org. Lett. 2003, 5, 3663. 被引量:1
  • 3[3]Keith, J. M.; Jacobsen, E. N. Org. Lett. 2004, 6, 153. 被引量:1

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