摘要
目的 建立反相高效液相色谱法测定醋酸地塞米松软膏含量的方法。方法 反相高效液相色谱法 ,C1 8柱 ,流动相为甲醇∶水 (70∶30 ) ,检测波长 2 4 0nm。结果 醋酸地塞米松在 1 3～ 2 0 8mg·L-1 内线性关系良好 ,r =0 9999,平均回收率 99 1 4 %(n =6 ,RSD =0 5 0 % )。结论 此法简便 ,快速 ,专属性强 。
Aim An RP HPLC method for the determinaton of dexamethasone acetate in dexamethasone acetate onitment was established. Method An elite C 18 was used, with the mobile phase of methanol water(70∶30) and the flow rate 0 7 ml·min -1 ,at the detection wavelength of 240 nm.Result The standard curve was linear in the range of 1 80～28 8 mg·L -1 of dexamethasone acetate with correlation coefficient of 0 999 9,the average recovery was 99 14%( n=6 ,RSD=0 50%).Conclusion The method was simple, quick, specific and accurate.
出处
《安徽医药》
CAS
2004年第5期367-368,共2页
Anhui Medical and Pharmaceutical Journal
