摘要
目的探讨维持内环境稳定对治疗重症急性胰腺炎的价值。方法对收治的SAPA(1990年前,手术为主治疗,131例)、B(1991￣1996年间,手术向非手术过渡,72例)、C(1997年后,非手术为主,105例)三组病例进行回顾性对照比较。结果A组住院时间、并发症发生率、死亡率为(41.18±29.73)d、67.93%和25.19%;B组为(31.83±14.97)d、50.00%和13.89%;C组为(16.83±6.11)d、30.50%和6.67%。结论维持内环境稳定是治疗SAP的核心,也是非手术为主治疗SAP的理论支柱。调控炎症反应适度,对防止MODS,降低SAP急性反应期高死亡率具有关键作用,应成为维持内环境稳定的重点。
[Objective] To investigate the value of maintaining inner environment stabilization for treating severe acute pancreatitis (SAP). [Methods] The clinical data of 308 patients with severe acute pancreatitis, had been divided into group A (131 cases, treated with operation before 1990), B (72 cases, treated with operation or no-operation between 1991~1996), and C (105 cases, treated with no-operation after 1997), according to the in hospital time, and analyzed retrospectively. [Results] In hospital time, complications occurring rate and mortality were separately (41.18±29.73) days, 67.93%, 25.19% in group A; (31.83±14.97) days, 50.00%, 13.89% in group B; and (16.83±6.11) days, 30.50%, 6.67% in group C. [Conclusions] Maintaining inner environment stabilization is the core to treate SAP. It is the key step for reducing SAP mortality that moderation manipulation of the inflammatory response to prevent multiple organ dysfunction syndrome, and so should be look as an important strategy.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2006年第24期3762-3764,共3页
China Journal of Modern Medicine
关键词
重症急性胰腺炎
治疗
severe acute pancreatitis
treatment
