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超声引导下注射新型泡沫硬化剂治疗大隐静脉曲张 被引量:5

Injection of a new foam sclerosing agent in treatment of incompetent great saphenous vein under guidance of ultrasound
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摘要 目的观察超声引导下注射新型泡沫硬化剂治疗大隐静脉曲张的短期疗效。方法对无深静脉及交通支静脉功能不全的重度大隐静脉曲张40条患肢(38例患者,其中2例为双下肢大隐静脉曲张),在超声引导下注射新型泡沫硬化剂FibroVein对大隐静脉主干进行硬化治疗。结果40条患肢均在超声引导下注射治疗成功,7条(7/40)大隐静脉于治疗后1个月复诊时实施了第2次注射治疗。随访1~12个月,全部患者(包括经2次治疗者)下肢活动后酸胀、乏力消失;下肢明显曲张畸形的静脉消失,其中8条(8/40)患肢远端存在局限性轻度曲张的静脉;无严重并发症发生。术后3个月复查彩色多普勒超声显示,曲张的大隐静脉较治疗前变细,22条(22/40)治疗大隐静脉的部分血管段实变,18条(18/40)静脉壁回声增强,并可见不规则、不均质中等实性回声紧密黏附于血管壁,挤压远端肢体时管腔内可见流沙样缓慢流动的血流信号,其中8条静脉(8/18)有少量反流。结论超声引导下注射新型泡沫硬化剂治疗大隐静脉曲张方便、有效、痛苦小、无瘢痕形成、无严重并发症,可重复进行,近期疗效佳,是一种治疗与美容兼备的微创治疗方法。 Objective To study sclerotherapy of great saphenous vein (GSV) with a new foam sclerosing agent (Fibro-Vein) made of purified sodium tetradecyl sulfate (SFT) under the guidance of ultrasound. Methods Thirty eight patients’ 40 incompetent GSVs were sclerosed using SFT under ultrasound guidance. The foam was obtained by mixing one part liquid SFT and four parts air, and was formed with a three-way stopcock and two syringes. The concentrations of SFT was 1.5% and the foam dose we used was 4~8 ml for every leg. Results Fourty varicosis of GSVs were treated successfully and seven of the GSVs (7/40) were treated again at 1-month follow-up. At 3-month follow-up, twenty two of the GSVs (22/40) were obliterated. Eighteen of the GSVs (18/40) showed cephalad blood flow when the distal part of the leg was squeezed; the wall of the GSV were thickened; there were homogeneous intraluminal echoic materials; eight of them (8/18) had slight reflux. Conclusions The sclerotherapy of GSV with a new kind of sclerosing agent made of purified SFT under the guiding of ultrasound is effective, convenient, and no scar formed. The early therapeutic effect was good without serious complications. The long-term effect of this group should be validated by fellow-up study.
出处 《中华医学超声杂志(电子版)》 2006年第4期207-209,共3页 Chinese Journal of Medical Ultrasound(Electronic Edition)
关键词 隐静脉 静脉曲张 硬化溶液 彩色多普勒超声检查 Saphenous vein Varicose veins Sclerosing solutions Color Doppler ultrasonography
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