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大剂量纳洛酮配合机械通气雾化戊乙奎醚救治急性有机磷中毒中间综合征的临床研究 被引量:2

Clinical study of hyperdose naloxone and penehyclidine with mechanical ventilation in the treatment of acute organophoshorus Poisoning with intermediate syndrome
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摘要 目的 观察大剂量纳洛酮配合机械通气雾化戊乙奎醚救治急性有机磷中毒中间综合征(IMS)的效果.方法 在内科综合治疗基础上,以大剂量纳洛酮(商品名:苏诺)配合机械通气雾化戊乙奎醚(商品名:长效托宁)救治IMS患者57例,计算病死率,并与国内外文献报道病死率进行比较.结果 病死率为40.36%,明显低于国内外文献报道62.5%死亡率(P<0.05) 结论:本疗法可提高抢救成功率,是救治急性有机磷中毒中间综合征的新途径,值得临床推广应用. Objective To observe the therapeutic effect of hyperdose naloxone and penehyclidine with mechanical ventilation in the treatment of acute Organophosphorus poisoning with intermediate syndrome. Methods 57cases of acute organophosphorus poisoning with intermediate syndrome were treated with hyperdose naloxone (sunno) and penehyclidine(Long-acting Tuoning) with mechanical ventilation besides medical therapy.The mortality was determined and compared with that issued by people family and abroad. Results The overall mortality was 40.36%,and the outcome was significantly lower as compared with that it were researched 62.5% by people family and abroad(<P0.05) .Conclusion It is suggested by the result that the new measures were successfully and may be a new way for acute organophosphorus poisoning with intermediate syndrome. The method is applied widespreadly in the work of clinical.
出处 《中外医疗》 2007年第23期36-37,共2页 China & Foreign Medical Treatment
关键词 急性有机磷中毒 中间综合征 纳洛酮 戊乙奎醚 机械通气 Acute organophosphorus poisoning.Intermediate syndrome.Naloxone.Penehyclidine.Mech anical ventilation.
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