摘要
复发性流产相关的止血功能异常包括遗传性、获得性以及联合功能异常。止血功能异常的类型与复发性流产的发生具有时段及频率的关联性。迄今为止,止血功能异常作为不明原因流产的重要危险因素仍存在争议,需要循证医学的研究进一步证实。预防性抗凝仅可用于有止血功能异常和不明原因流产的妇女,而抗凝治疗对预防复发性流产发生的益处还需要随机对照研究进一步证实。
Recent research shown that dysfunction of homeostasis associated with recurrent spontaneous abortion(RSA) includes inherited,acquired,and combined dysfunction of homeostasis.The type of dysfunction of homeostasis has certain relation to frequency of RSA and gestational age when RSA occurs.Up to now,whether dysfunction of homeostasis can be regarded as an important risk factor of unexplained miscarriage is controversial,which needs to be confirmed by evidence medical research.Prophylactic antithrombotic treatment is approval to be used only for selected women with dysfunction of homeostasis and unexplained recurrent spontaneous abortion,but the benefits of antithrombotic treatment for RSA still need to be further proved by randomized control study.
出处
《中国妇幼健康研究》
2007年第5期421-423,共3页
Chinese Journal of Woman and Child Health Research
关键词
止血功能异常
遗传性
获得性
复发性流产
预防性抗凝
dysfunction of homeostasis
inherited
acquired
recurrent spontaneous abortion
prophylastic antithrombotic treatment