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氧化应激导致2型糖尿病患者的内皮祖细胞的在体再内皮化能力受损:过氧化物酶体增生物激活受体-γ促进剂罗格列酮的修复作用 被引量:1

Oxidant stress impairs in vivo reendothelialization capacity of endothelial progenitor cells from patients with type 2 diabetes mellitus:Restoration by the peroxisome proliferator-activated receptor-γ agonist rosiglitazone
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摘要 背景:内皮祖细胞(EPC)被认为可促进动脉损伤后内皮恢复。因此比较了来源于糖尿病患者和健康受试者的EPC的在体再内皮化能力。此外。 BACKGROUND-Endothelial progenitor cells(EPCs) are thought to contribute to endothelial recovery after arterial injury. We therefore compared in vivo reendothelialization capacity of EPCs derived from patients with diabetes mellitus and healthy subjects. Moreover, we examined the effect of treatment with the peroxisome proliferator-activated receptor-γagonist rosiglitazone on oxidant stress, nitric oxide(NO) bioavailability, and the in vivo reendothelialization capacity of EPCs from diabetic individuals. MET...
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