摘要
目的:半胱氨酸蛋白酶抑制剂C是一个评价肾功能的新指标,被认为是心血管疾病的预后标记物。本研究探讨半胱氨酸蛋白酶抑制剂C与其他肾功能指标及NT-proBNP相比,在急性心力衰竭患者中的预后预测价值。方法和结果:纳入一项前瞻性、多中心的急性心力衰竭研究中测定了半胱氨酸蛋白酶抑制剂C水平的480例患者。12个月全因死亡率为25.4%。
Aims: Cystatin C, a novel marker of renal function, has been implicated as a prognostic marker in cardiovascular disease. We investigated the prognostic value of cystatin C in acute heart failure(AHF) in comparison to other markers of renal function and NT-proBNP.Methods and results: Patients with cystatin C measurements(n=480) from a prospective multicentre study on AHF were included. All-cause mortality at 12 months was 25.4% . Cystatin C, creatinine, age, gender, and systolic blood pressure on admission ...
