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基于人群的乳糜泻住院患者队列中的血管疾病

Vascular disease in a population-based cohort of individuals hospitalised with coeliac disease
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摘要 目的:评价乳糜泻(CD)患者发生心血管疾病的风险。设计:使用瑞典国立医院注册资料识别了13358例已诊断为CD(1964—2003)的患者以及64118例年龄及性别相匹配、未患CD的个体。使用Cox回归评估CD患者发生血管疾病的风险。分析仅限于那些随访超过1年且在入选前没有血管疾病的个体。结果:CD与心肌梗死(HR1.27,95%CI1.09~1.48)、 Objectives: To evaluate the risk of cardiovascular disease in individuals with coeliac disease(CD). Design: Swedish national hospital-based register data were used to identify 13 358 individuals who had been diagnosed with CD(1964- 2003) and 64 118 age-matched and sex-matched individuals without CD.Cox regression was used to estimate the risk of vascular disease in subjects with CD. Analyses were restricted to individuals with a follow-up of >1 year and with no vascular disease before study entry. Result...
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