期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

不同时期糖尿病肾病患者血清超敏C-反应蛋白检测

Determination of Serum Highly Sensitive C-reactive Protein in Pa-tients with Different Phase Diabetic Nephropathy .
下载PDF
导出
摘要 目的探讨血清超敏C-反应蛋白(hsCRP)水平与糖尿病肾病(diabeticnephropathy,DN)发展的关系。方法120例DN患者根据尿白蛋白排泄率分为正常蛋白尿组、微量白蛋白尿组和临床蛋白尿组,测定血清hsCRP、血甘油三脂(TG)、肌酐(Cr)、尿白蛋白(UA),以40名正常人为对照组。结果DN各组hsCRP、TG、Cr、UA均高于对照组,DN各组间hsCRP水平有显著差异(P0.05)。结论在DN的发展过程中有炎症因素参与,hsCRP为一危险因子,其水平可提示DN的损害程度。 Objective To investigate the relationship between serum level of highly sensitive C- reactiveprotein(hsCRP) and the development of diabetic nephropathy .Methods 120 patients with diabetic nephropathy( DN)were divided into three groups base in urine albumin excretion rate( UAER ),the normal proteinuria group (n=40)、the microalbuminuria group (n=40) and the clinical proteinuria group(n=40).70 healthy individuals were normalcontrols.Measured serum hsCRP 、Trioleate glyceryl (TG) 、 Creatinine(Cr)、Urinary albumin...
作者 覃丹平 邬刚 刘岩 卢智 钟小仕 周道远
机构地区 暨南大学医学院附属第四医院(广州市红十字会医院)肾内科 南方医科大学分校内科教研室
出处 《国际医药卫生导报》 2006年第6期82-83,共2页 International Medicine and Health Guidance News
关键词 糖尿病肾病 超敏C-反应蛋白 diabetic nephropathy high sensitive C-reactive protein
分类号 R692 [医药卫生—泌尿科学]
  • 相关文献

参考文献8

  • 1[1]Spranger J,Kroke A,Mohlig M,et al.Inflammatory cytokines and the risk to devdlop type 2 diabetes:results of the prospective populationbased European Prospective Investigation into Cancer and Nutrition(EPIC)-Potsdam Study.Diabetes,2003,52(3):812-817 被引量：1
  • 2[2]Pradhan AD,Manson JE,Rifai N,et al.C-reactive protein,interleukin 6,and risk of developing type2 diabetes mellitus.JAMA,2001,286(3):327-334 被引量：1
  • 3[3]Barzilay JI,Abraham L,Heckbert SR,et al.The relation of markers of inflammastion to the deveplopment of glucose disorders in the elderly:the cardiovascular health studay.Diabetes,2001,50(10):2384-2389 被引量：1
  • 4晨钟,薛耀明,高方,汪敏.2型糖尿病患者血清超灵敏C反应蛋白水平的检测[J].第一军医大学学报,2004,24(7):791-793. 被引量：7
  • 5[5]Yoshimasa Aso,Noboru Yoshida,Ki-ichi Okumura,et al.Result of blood inflammatory markers are associated more strongly with toe-brachia1 index than with ankle-brachial index in patients with type 2 diabetes.Diabetes care,2004,27(6):1381-1386 被引量：1
  • 6[6]Kunsch C,Medford RM..Oxidative stress as a regulator of gene expression in the vasculature.Cire Res,1999,85(8):753-766 被引量：1
  • 7[7]Erbagel A,Tarakcioglu M,Coskum Y,et al.Mediators of inflammation in children with type ldiabetes mellitus:cytokines in type ldiabetic children.Clin Biochem,2001,34:645-650 被引量：1
  • 8吴恒莲,林宏初,陈月影,刘国辉,张秀薇,阮雪玲,区冰玲,郑东文,彭伟成,黄娇平,张丽梅.氟伐他汀治疗早期糖尿病肾病疗效分析[J].中国实用内科杂志,2004,24(8):486-487. 被引量：18

二级参考文献11

  • 1[1]Barzilay JI,Abraham L,Heckbert SR,et al.The relation of markers of inflammation to the development of glucose disorders in the elderly:the cardiovascular health study.Diabetes,2001,50(10):2384-2389 被引量：1
  • 2[2]Romano M,Pomilio M,Vigneri S,et al.Endothelial perturbation in children and adolescents with type 1 diabetes:association with markers of the inflammatory reaction.Diabetes Care,2001,24(9):1674-1678 被引量：1
  • 3Rodriguez-Moran M; Guerrero-Romero F. Increased levels of C-reactive protein in non-controlled type Ⅱ diabetic subjects [J]. J Diabetes Complications, 1999, 13(4): 211-5. 被引量：1
  • 4Barzilay JI, Abraham L, Heckbert SR, et al. The relation of markers of inflammation to the development of glucose disorders in the elderly: the cardiovascular health study [ J ]. Diabetes, 2001, 50 (10):2384-9. 被引量：1
  • 5Pradhan AD, Manson JE, Rifai N, et al. C-reactive protein. interleukin 6, and risk of developing type 2 diabetes mellitus [J ]. JAMA,2001, 18, 286(3): 327-34. 被引量：1
  • 6Forouhi NG, Satter N, McKeigue PM. Relation of C-reactive protein to body distribution and feature of the metabolic syndrome in Europeans and South Asians[J]. Int J Obes Relat Metab Disord, 2001, 25(9): 1327-31. 被引量：1
  • 7Moro E, Gallina P, Pais G, et al. Hypertriglyceridemia is associated with increased insulin resistance in subjects with normal glucose tolerance: evaluation in a large cohort of subjects assessed with 1999World Health Organization criteria for the classification of diabetes[J]. Metabolism, 2003, 52(5): 616-9. 被引量：1
  • 8Haffner SM, Mykkanen L, Festa A, et al. Insulin-resistant prediabetic subjects have more atherogenic risk factors than insulin-sensitive prediabetic subjects[J ]. Circulation, 2000, 101: 975-80. 被引量：1
  • 9Kelly CC, Lyall H, Petrie JR, et al. Low grade chronic inflammation in women with polycystic ovarian syndrome [J]. J Clin Endocrinol Metab, 2001, 86(6): 2453-5. 被引量：1
  • 10Pannacciuilli N, Cantatore FP, Minenna A, et al. C-reactive protein is independent associated with total body fat, center fat, and insulin resistance in adult women[J]. Int J Obes Relat Metab Disord, 2001, 25(10): 1416-20. 被引量：1

共引文献23

国际医药卫生导报
2006年 第6期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部