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肾移植术后糖尿病诱发因素分析 被引量:4

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摘要 目的:探讨肾移植术后糖尿病(PTDM)的危险因素及有效治疗。方法:对比分析肾移植后糖尿病26例与同期非肾移植后糖尿病(DPTDM)187例临床资料。结果:肾移植213例中发生肾移植后糖尿病26例(12.2%),发生在术后6个月内17例(65.4%)。肾移植术后糖尿病发病以高龄、高体重及肝肾功能异常[(26.9±1.5%)及(42.3±2.3%)]者更多见,同时也与糖皮质激素的大量应用有关。而6个月后与他克莫司和环孢素A应用有关,二者间他克莫司对血糖影响更大。早期发生者以胰岛素注射为主,移植手术6个月后发生的糖尿病患者接受口服降糖药为主,辅以饮食控制。结论:肾移植术后糖尿病是一种与抗排异药物及移植肾功能密切相关的继发性糖尿病。应引起临床足够重视,并进行积极有效地治疗。
出处 《南通大学学报(医学版)》 2008年第3期199-200,共2页 Journal of Nantong University(Medical sciences)
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参考文献5

  • 1[1]Numakura K,Satoh S,Tsuchiya N,et al.Ciinical and genet-ic risk factors for posttransplant diabetes mellitus in adult renal transplant recipients treated with tacrolimus[J].Transplantation,2005,80(10):1419-1424. 被引量:1
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二级参考文献14

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