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内镜辅助和胸壁入路内镜甲状腺切除术与传统甲状腺切除术的比较 被引量:10

Comparison of Endoscopic-assisted, Transthoracic Endoscopic, and Conventional Techniques for Thyroidectomy
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摘要 目的比较内镜辅助及胸壁入路内镜甲状腺切除术与传统甲状腺切除术创伤程度、术后疼痛、美容效果及2种内镜术式的各自特点。方法45例甲状腺结节按入院顺序分成3组,每组15例,分别行内镜辅助甲状腺切除术(endoscopicassisted thyroidectomy,EAT)、胸壁入路内镜甲状腺切除术(transthoracic endoscopic thyroidectomy,TET)及传统甲状腺切除术(conventional thyroidectomy,CT)。检测术前及术后24、72h血清CRP、IL-6、TNF-α、T淋巴细胞亚群(CD3,CD4+,CD8+,CD4+/CD8+)水平,评估手术创伤程度,视觉模拟评分法评估术后疼痛感受,5级评价法评估术后美容满意度。结果VAS疼痛评分:术后第1、3天EAT组分别为2.2±1.7、1.1±1.1,明显轻于TET组3.6±1.4、2.2±0.7(第1天q=3.698,P<0.05;第3天q=4.824,P<0.05)和CT组4.6±1.0、3.0±0.8(第1天q=6.339,P<0.05;第3天q=8.332,P<0.05)。美容满意度调查EAT、TET、CT组十分满意分别为1、10、0例;满意分别为13、5、4例;一般分别为1、0、11例,TET组和EAT组均明显优于CT组(z=-3.386,P=0.000;z=-3.676,P=0.000),TET组最佳(z=-4.513,P=0.000)。除CT组手术前后CD4+/CD8+有统计学差异外(F=4.47,P=0.014),3组血清IL-6、TNF-α、T淋巴细胞亚群水平(CD3,CD4+,CD8+)手术前后及组间比较差异均无显著性(P>0.05),CT组术后24h CD4+/CD8+较术前降低(q=4.076,P<0.05),术后72h恢复接近术前水平(q=0.705,P>0.05)。3组CRP水平术后24、72h均较术前明显升高(EAT组m=21,P<0.001;m=24,P<0.001;TET组m=22,P<0.001;m=23,P<0.001;CT组m=21,P<0.001;m=24,P<0.001),但3组间比较差异无显著性(P>0.05)。结论EAT组术后疼痛轻、恢复快、美容效果较好,更具微创手术特征;TET组美容效果理想,未发现TET组比CT组有更严重的创伤反应。 Objective To compare the degree of trauma, postoperative pain, and cosmetic outcomes of endoscopic-assisted thyroidectomy (EAT), transthoracic endoscopic thyroidectomy (TET), and conventional thyroidectomy (CT), and to explore the characteristics of EAT and TET. Methods Forty-five patients with thyroid nodules were divided into three groups (n=15 in each) to underwent EAT, TET, or CT. The plasma levels of C-reactive protein(CRP), interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α), and T-lymphocyte su...
出处 《中国微创外科杂志》 CSCD 2008年第1期56-60,共5页 Chinese Journal of Minimally Invasive Surgery
关键词 甲状腺切除术 内镜 胸壁入路 Thyroidectomy Endoscopy Transthoracic approach
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参考文献18

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