摘要
目的探讨肝移植治疗肝细胞型肝癌的临床价值及影响预后的因素。方法对67例接受肝移植治疗、且随访时间≥6个月的肝细胞型肝癌患者的临床资料进行回顾性分析。结果67例患者肝移植术后1年、2年存活率分别为89.96%、65.59%,1年、2年无瘤存活率分别为77.51%、62.49%;单因素分析显示,甲胎蛋白水平、肿瘤最大直径、门静脉癌栓、肿瘤累及肝脏左右两叶、肿瘤分化程度和肿瘤TNM分期是影响无瘤存活率的重要因素,Cox风险模型多因素分析显示,肿瘤最大直径和门静脉癌栓是影响无瘤存活率的独立危险因素。结论肝移植是目前治疗肝细胞型肝癌的有效方法,肿瘤直径>5cm和门静脉癌栓严重影响患者的无瘤存活率。
Objective To evaluate the clinical value and prognostic factors of orthotopic liver transplantation (OLT) for hepatocellular carcinoma (HCC). Methods Sixty-seven HCC patients undergoing OLT in our hospital were followed up more than 6 months. Their clinical and follow-up data were retrospectively analyzed. Results The 1- and 2-year cumulative survival rate of the 67 patients was 89.96 % and 65.59 % respectively. The 1- and 2-year tumor-free survival rate was 77.51 % and 62.49 % respectively. Univariate anal...
出处
《中华器官移植杂志》
CAS
CSCD
北大核心
2005年第7期417-419,共3页
Chinese Journal of Organ Transplantation
基金
上海市科委重大项目(024119001)
上海市跨世纪医苑新星培养计划项目(沪卫医政1999-59号)
关键词
肝移植
癌
肝细胞
药物疗法
联合
Liver transplantation
Carcinoma
hepatocellular
Drug therapy
combination
