摘要
目的了解我院3年来血液标本的培养结果及药敏状况,以指导临床合理使用抗生素。方法采用BacT/Alert120血培养仪及梅里埃公司的API系统和VITEK2系统阳性标本进行菌种鉴定和药物敏感试验,用WHONET5.3软件进行分析。结果6268份血标本中,检出细菌1064株,检出率为16.6%,其中革兰阳性菌占55.4%,革兰阴性菌占38.1%,真菌占6.5%。未发现对万古霉素耐药的葡萄球菌和肠球菌;有19.2%的大肠埃希菌和3.3%的肺炎克雷伯菌产超广谱β-内酰胺酶;鲍曼不动杆菌的耐药发展日趋明显;真菌的检出数量增多不容忽视。结论我院引起菌血症的主要病原菌仍以革兰阳性球菌为主,及时了解血培养结果为临床有针对性地抗菌治疗提供依据,降低病死率,提高治愈率。
Objective To investigate the clinical infection and the antimicrobial resistance of bacteria separated from blood samples in our hospital from Jan.2002 to Jun.2005.Methods bacteria had been identified by French API and VITEK2 system,and been tested by K-B method from clinical samples.The results of the resistance rates were analyzed though the WHONET5.3 software.Results From 1064 stains of bacteria,Gram positive cocci,Gram negative bacilli and fungi accounted for 55.4%,38.1% and 6.5%.No stains resistant to vancomycin was found in staphylococci and enterococci.ESBLs-producing Eco and Kpn was 19.2% and 3.3%.The ascending resistant tendency of aba was more remarkable.The infection of fungi should not be ignored.Conclusion The main bacteria separated from blood samples was Gram positive cocci.Timely identification of bacteria and exact results of antibiotic susceptivity tests could provide significant test evidence to clinical treatment,and enhance rate of cure.
出处
《中国实验诊断学》
2007年第11期1517-1519,共3页
Chinese Journal of Laboratory Diagnosis
关键词
血培养
菌血症
耐药性
Blood culture
Baceteremia
Antimicrobial resistance
