摘要
目的评估慢性肾衰竭患者的颈动脉粥样硬化并分析其影响因素。方法回顾性分析148例慢性肾衰竭患者的临床资料,统计高频彩超下颈动脉粥样硬化发生率,并对其影响因素进行Logistic回归分析。结果共有97例发生颈动脉粥样硬化,发生率为65.54%。硬化组和未硬化组在性别、透析方法方面的差异无统计学意义(P>0.05)。硬化组的以下指标水平明显高于未硬化组(P<0.05):年龄>60岁、身体质量指数(BMI)>25 kg/m^(2)、综合性营养评估法(GNA)≥7.5分、吸烟包年≥5年、糖尿病、高血压、高血脂、高尿酸血症、肾功能衰竭病程≥3年、透析时间>1年。Logistic回归分析显示,以下指标是肾衰竭患者颈动脉粥样硬化的影响因素:年龄>60岁、BMI>25 kg/m^(2)、GNA≥7.5分、吸烟包年≥5年、糖尿病、高血压、高血脂、高尿酸血症、肾功能衰竭病程≥3年、透析时间>1年。结论慢性肾衰竭患者颈动脉粥样硬化的患病率为65.54%,年龄>60岁、BMI>25 kg/m^(2)、GNA≥7.5分、吸烟包年≥5年、糖尿病、高血压、高血脂、高尿酸血症、肾衰竭病程≥3年和透析时间>1年与慢性肾衰竭患者较高的颈动脉粥样硬化的患病率密切相关。
Objective To evaluate carotid atherosclerosis in patients with chronic renal failure and analyze its influencing factors.MethodsThe clinical data of 148 patients with chronic renal failure were analyzed retrospectively.The incidence of carotid atherosclerosis under high-frequency color Doppler ultrasound was calculated,and the influencing factors were analyzed by logistic regression.ResultsThere were 97 cases of carotid atherosclerosis with an incidence of 65.54%.There was no statistically significant difference between the sclerotic group and the non-sclerotic group in gender and dialysis method(P>0.05).The sclerotic group was significantly higher than the non-sclerotic group in the following indicators(P<0.05),including age>60 years,body mass index(BMI)>25 kg/m^(2),general nutrition assessment(GNA)≥7.5 points,smoking package≥5 years,diabetes,hypertension,hyperlipidemia,hyperuricemia course of renal failure≥3 years,dialysis time>1 year.Logistic regression analysis showed that the following indicators were influencing factors of carotid atherosclerosis in patients with renal failure,including age>60 years,body mass index(BMI)>25 kg/m^(2),global nutrition assessment(GNA)≥7.5 points,smoking package≥5 years,diabetes,hypertension,hyperlipidemia,hyperuricemia course of renal failure≥3 years,and dialysis time>1 year.ConclusionThe prevalence of carotid atherosclerosis in patients with chronic renal failure was 65.54%.The factors including age>60 years,BMI>25 kg/m^(2),GNA≥7.5 points,smoking package years≥5 years,diabetes,hypertension,hyperlipidemia,hyperuricemia,renal failure course≥3 years,and dialysis time>1 year were closely related to the higher prevalence of carotid atherosclerosis in patients with chronic renal failure.
作者
徐敏
赖仕峰
罗娜
李慧敏
Min Xu;Shifeng Lai;Na Luo;Huimin Li(Jianyang People′s Hospital,Jianyang 641400,Sichuan Province,China)
出处
《中华肾病研究电子杂志》
2022年第6期307-310,共4页
Chinese Journal of Kidney Disease Investigation（Electronic Edition）
关键词
慢性肾衰竭
颈动脉粥样硬化
影响因素
高频彩超
Chronic renal failure
Carotid atherosclerosis
Influencing factors
High frequency color ultrasound
