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肌肉减少症与肝癌研究进展

Research progress of sarcopenia and liver cancer
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摘要 肌肉减少症是一种进行性的全身骨骼肌质量下降和功能减退的临床综合征,与多种疾病的不良临床结局相关。临床中有11%~45%的肝癌患者存在肌肉减少症。肝癌关肌肉减少症的原因是多种因素共同作用的结果,目前发病机制尚不清楚。肌肉减少症对肝癌治疗的临床结局和预后都有明显的影响。通过从营养、运动、药物等方面治疗肝癌相关肌肉减少症,可改善肝癌患者的临床结局和预后。 Sarcopenia is a syndrome associated with low muscle mass and muscle strength,and it is related to adverse outcomes in a variety of diseases.Sarcopenia occurs in 11%to 45%of liver cancer patients.The cause of liver cancer associated sarcopenia is the result of many factors,and the pathogenesis is still unclear.Sarcopenia has significant influence on the clinical outcome and prognosis of liver cancer.Thus,the clinical outcome and prognosis of patients with liver cancer can be improved by the intervention of sarcopenia from the aspects of nutrition,exercise,and medicine.
作者 马金栋 焦向飞 蔡婷婷 陈强谱 Ma Jingdong;Jiao Xiangfei;Cai Tingting;Chen Qiangpu(Department of Hepatobiliary Surgery,Affiliated Hospital of Binzhou Medical College,Binzhou 256600,China;Department of clinical nutrition,Affiliated Hospital of Binzhou Medical College,Binzhou 256600,China)
出处 《中华临床医师杂志(电子版)》 CAS 北大核心 2023年第3期356-359,共4页 Chinese Journal of Clinicians(Electronic Edition)
基金 山东省省级临床重点专科建设基金资助项目(SLCZDZK-0701) 山东省省级临床重点专科建设基金资助项目(SLCZDZK-2401)
关键词 肌肉减少症 肝癌 预后 并发症 生存时间 Sarcopenia Liver cancer Prognosis Complications Survival time
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