摘要
目的探讨经皮冠状动脉旋磨术应用于冠状动脉重度钙化病变介入治疗的效果。方法选取2020年4月至2022年3月济宁医学院附属高唐县人民医院收治的107例需接受经皮冠状动脉介入治疗(PCI)的冠状动脉重度钙化病变患者,其中53例给予单纯PCI(对照组),54例在对照组基础上给予经皮冠脉旋磨术治疗(观察组),观察比较两组患者介入治疗相关指标、心功能情况、并发症及主要心血管不良事件发生情况。计量资料的比较采用t检验,计数资料的比较采用χ^(2)检验。结果两组患者球囊用量和预扩张次数的差异均有统计学意义(t=3.969、5.625,P<0.01)。两组患者治疗后左室舒张末期和收缩末期容积均较治疗前降低,左室射血分数均升高,但治疗前后组间差异均无统计学意义(P>0.05)。两组患者并发症和主要心血管不良事件发生率的差异均无统计学意义(χ^(2)=0.976、0.853,P>0.05)。结论对于行PCI的冠状动脉重度钙化病变患者,使用经皮冠状动脉旋磨术具有良好的治疗效果和安全性。
Objective To explore the effectiveness of percutaneous coronary rotational atherectomyin the interventional treatment of severe coronary artery calcification lesions.Methods A total of 107 patients with severe coronary artery calcification requiring percutaneous coronary intervention(PCI)admitted to Gaotang County Hospital affiliated with Jining Medical College from April 2020 to March 2022 were selected.Among them,53 patients were treated with PCI(control group),and 54 patients were treated with percutaneous coronary rotational atherectomy in addition(observation group).The intervention related indicators,cardiac function,and the occurrence of complications and major cardiovascular adverse events were observed.T test was used for comparison of measurement data,and χ^(2) test was used for comparison of counting data.Results The differences in balloon dosage and pre dilation frequency between the two groups were statistically significant(t=3.969,5.625;P<0.01).After treatment,left ventricular end diastolic volume and left ventricular end systolic volume of both groups decreased compared with before treatment,while left ventricular ejection fraction increased.However,there was no statistically significant difference between the two groups before and after treatment(P>0.05).There was no statistically significant difference in the incidence of complications and major cardiovascular adverse events between the two groups(χ^(2)=0.976,0.853;P>0.05).Conclusion For patients with severe coronary artery calcification undergoing PCI,the use of coronary rotational atherectomy has good interventional effects and safety.
作者
孙相利
许真真
Sun Xiangli;Xu Zhenzhen(Department of Cardiology,Gaotang County people's Hospital Affiliated to Jining Medical College,Jining 252800,China)
出处
《中华老年病研究电子杂志》
2023年第2期33-36,共4页
Chinese Journal of Geriatrics Research(Electronic Edition)
关键词
冠状动脉重度钙化病变
经皮冠状动脉旋磨术
冠状动脉介入治疗
主要心血管不良事件
Severe calcification of coronary artery
Percutaneous coronary rotational atherectomy
Percutaneous coronary interventional
Major cardiovascular adverse events