摘要
目的:比较国产角膜地形图仪Scansys与三维眼前节分析仪Sirius测量近视患者与圆锥角膜患者眼前节参数的一致性和差异性。方法:回顾性临床研究。随机纳入2021年7月至2022年3月在湖南省人民医院眼视光中心进行近视术前检查的患者96例(96眼)和圆锥角膜患者61例(61眼)。分别使用Scansys和Sirius测量患者角膜直径(WTW)、前房深度(ACD)、角膜曲率平坦轴(Kf)、角膜曲率陡峭轴(Ks)、角膜平均曲率(Km)、中央角膜厚度(CCT)、角膜最薄点厚度(TCT)并进行比较。采用配对t检验、Pearson相关分析与Bland-Altman图检测2种仪器结果的差异性、相关性和一致性。结果:与Sirius相比,2组患者中,Scansys测量的CCT、TCT较厚,WTW较小,ACD较浅,Kf、Ks、Km较高,差异均有统计学意义(t_(CCT)=10.42、7.90,均P<0.001;t_(TCT)=9.53、5.60,均P<0.001;t_(WTW)=-17.17、-8.42,均P<0.001;t_(ACD)=-12.93、-4.99,均P<0.001;t_(Kf)=5.20、2.30,P<0.001、P=0.025;t_(Ks)=6.67、4.47,均P<0.001;t_(Km)=6.89、2.97,P<0.001、P=0.004)。近视患者中,2种仪器WTW差值较大为(-0.45±0.26)mm。2种仪器间测量的眼前节参数相关性较好,呈正相关(均r>0.78,P<0.001)。Bland-Altman一致性分析2种仪器测量近视患者与圆锥角膜患者的ACD、TCT一致性好,测量ACD的95%一致性界限(LoA)分别为-0.23~0.05、-0.09~0.09 mm,测量TCT的95%LoA分别为-2.20~15.48、-3.57~14.43 mm。测量近视患者WTW一致性较差,95%LoA为-0.96~0.06 mm。在角膜曲率(Kf、Ks、Km)的测量中,与近视患者相比,2种仪器测量圆锥角膜组患者的95%LoA略宽,一致性稍差。结论:Scansys与Sirius测量近视患者与圆锥角膜患者ACD、TCT、Kf、Ks、Km相关性及一致性较好,测量值可相互替代;测量近视患者WTW一致性较差,不建议数值相互替代。
Objective:To compare the consistency and differences in the measurement of ocular anterior segment parameters in patients with myopia and keratoconus using the domestic corneal topographer Scansys and the 3D ocular segment analyzer Sirius.Methods:This retrospective clinical study included 96 patients(96 eyes)with myopia and 61 patients(61 eyes)with keratoconus in the preoperative examination at the Optometry Center of Hunan Provincial People's Hospital from July 2021 to March 2022.Horizontal white-to-white(WTW),anterior chamber depth(ACD),flat axis of corneal curvature(Kf),steep axis of corneal curvature(Ks)and mean corneal curvature(Km),central corneal thickness(CCT),and thinnest corneal thickness(TCT)were measured using Scansys and Sirius,respectively.Paired t-test,Pearson correlation analysis,and Bland-Altman plot were used to detect the difference,correlation,and agreement in the results of two instruments.Results:Compared with Sirius,Scansys measured thicker CCT and TCT,smaller WTW,shallower ACD,and higher corneal curvature(Kf,Ks,Km)in both patient groups,with statistically significant differences(t_(CCT)=10.42,7.90,all P<0.001;t_(TCT)=9.53,5.60,all P<0.001;t_(WTW)=-17.17,-8.42,all P<0.001;t_(ACD)=-12.93,-4.99,all P<0.001;t_(Kf)=5.20,2.30,P<0.001,P=0.025;t_(Ks)=6.67,4.47,all P<0.001;t_(Km)=6.89,2.97,P<0.001,P=0.004).Among myopic patients,the difference of WTW between the two instruments was(-0.45±0.26)mm.The correlation between the anterior segment parameters measured by the two instruments was positive(all r>0.78,P<0.001).The Bland-Altman agreement analysis showed that ACD and TCT of myopic and keratoconic patients measured by the two instruments had good consistency.The 95%limits of agreement(LoA)for ACD was-0.23-0.05 mm and-0.09-0.09 mm,respectively.The 95%LoA for TCT was-2.20-15.48 mm and-3.57-14.43 mm,respectively.The consistency of WTW measurement was poorer in myopic patients,with 95%LoA ranging from-0.96 to 0.06 mm.Compared to myopic patients,in the corneal curvature(Kf,Ks,Km)measurements,the 95%LoA
作者
吴灏
钟定娟
陈蛟
罗栋强
陈果
王华
Hao Wu;Dingjuan Zhong;Jiao Chen;Dongqiang Luo;Guo Chen;Hua Wang(The First Affiliated Hospital of Hunan Normal University,Hunan Provincial People's Hospital Optometry Center,Changsha 410000,China)
出处
《中华眼视光学与视觉科学杂志》
CAS
CSCD
2023年第10期771-776,共6页
Chinese Journal Of Optometry Ophthalmology And Visual Science
基金
湖南省教育厅科学研究项目(22A0044)
