摘要
To the Editor:Systemic lupus erythematosus(SLE)is an autoimmune disease characterized by the production of various autoantibodies.Disease prevalence is 20 to 70 per 100,000 among adults,and 1.89 to 25.7 per 100,000 among children.[1,2]The pathogenesis of SLE is associated with immune disorders,especially involving the activation of B and T cells,which can lead to abnormal antibodies with nuclear and cytosolic antigens from apoptotic cells of the immune complexes(ICs)removing the damaged cells,and excessive activation of the complement system,thus causing damage to target organs,such as the kidneys and lungs.
