摘要
Introduction Urticaria is a common disease in dermatology.Physical urticarias are a group of urticaria that are induced by various physical stimulations,including shear force,cold,heat,pressure,and solar and vibratory stimulations.Cold contact urticaria (CCU),the second most common subtype among all physical urticarias in China,is characterized by itchy wheals and edema on skin following exposure to cold.The ice cube skin contact test is one of the most used methods by which to make the diagnosis of CCU[1].