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Analysis on relationship of parameters such as R5 and MEFV with severity of chronic cough in 3 to 5 years old children by impulse oscillometry detection

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摘要 Objective:The article aims to investigate the relationship of parameters such as airway vicosity resistance (R5) and maximal expiratory flow-volume curve (MEFV) with severity of chronic cough in 3 to 5 years old children by impulse oscillometry (IOS) detection when the oscillation frequency is 5Hz.Method: The article chooses eighty children with chronic cough who were diagnosed or treated in our hospital from March 2017 to March 2018 as the research group, and chooses 50 healthy children who had physical examination in our hospital as the control group. Children's asthma control test (C-ACT) is used to assess the disease severity of children. MEFV detection is carried out to the two groups of children to obtain the ratio of forced expiratory volume in one second and forced vital capacity (FEV1/FVC) and the peak expiratory flow (PEF). LsS inductance (X5) is detected by IOS when R5, the resonant frequency (Fres), and the oscillation frequency is 5Hz. The relationship of ACT score with MEFV and IOS indicators is analyzed by Pearson correlation. The receiver operating characteristic (ROC) curve is used to evaluate the diagnostic value of MEFV and IOS indicators to chronic cough. Results: The C-ACT score of the severe group is significantly lower than that of the control group (P<0.05). FEV1/FVC and PEF of the mild and severe groups are both lower than those of the control group, and FEV1/FVC and PEF of the severe group is lower than those of the mild group (P<0.05). Fres, R5 and X5 of the mild and severe groups are significantly higher than those of the control group, and Fres, R5 and X5 of the severe group are higher than the mild group (P<0.05). FEV1/FVC and PEF are positively correlated with C-ACT score (P<0.05), while Fres, R5 and X5 are negatively correlated with C-ACT score (P<0.05). FEV1/FVC and PEF respectively shows significant negative correlations with Fres, R5 and X5 (P<0.05). R5 has a self-high ROC value of 0.938, followed by Fres, which is 0.917. And the value of IOS diagnostic indicators is higher than
机构地区 Pediatrics
出处 《Journal of Hainan Medical University》 2019年第11期48-52,共5页 海南医学院学报(英文版)
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