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奥沙利铂联合替吉奥与FOLFOX4治疗晚期直肠癌疗效比较

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摘要 目的分析研究晚期直肠癌采用奥沙利铂联合替吉奥与FOLFOX4治疗的治疗效果。方法抽取2011年8月~2013年5月在我院收治的患有晚期直肠癌的患者100例,采用随机抽取模式,随机分为两组,每组各50例。对照组对患者实施FOLFOX4治疗,实验组对患者实施奥沙利铂联合替吉奥治疗,对两组患者近期临床治疗效果给予对比分析。结果实验组临床客观有效率56%,对照组临床观有效率52%,两组间差异不具有统计学意义(>0.05);实验组不良反应发生率6%,对照组不良反应发生率20%,临床实验结果显示,实验组不良反应发生率明显低于对照组(<0.05)。结论晚期直肠癌采取奥沙利铂联合替吉奥与FOLFOX4治疗的临床治疗效果都比较明显,其中奥沙利铂联合替吉奥不良反应明显少于FOLFOX4,因此,更加具有安全性,具有临床推广价值。
作者 侯晓玲
出处 《医学信息(医学与计算机应用)》 2014年第18期562-562,共1页 Medical Information
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