摘要
目的比较接种单剂吸附无细胞百白破联合疫苗(DTaP)、脊髓灰质炎灭活疫苗(IPV)及B型流感嗜血杆菌疫苗(Hib)与DTaP-IPV/Hib五联疫苗(简称五联疫苗)接种后的不良反应,探求更合理的免疫程序。方法在我院免疫接种的378例健康婴幼儿,按照监护人自愿原则分为两组,A组接种五联疫苗,B组接种DTaP、Hib结合疫苗和IPV,48 h后随访两组婴幼儿不良反应情况,并对两组不良反应进行对比分析。结果 A、B组注射部位红肿的发生率分别为16.5%、10.0%。全身不良反应主要表现为发热、异常哭闹、嗜睡、易激惹、食欲下降,A、B组的发生率相当。结论五联疫苗的不良反应与常规单剂免疫接种相似,它简化了免疫程序,应推荐接种。
Objective To compare single agent adsorption cellfree the DPT combined vaccine(DTaP)environments according,polio inactivated vaccine(IPV)and haemophilus influenzae type B(Hib)and DTaP vaccine-IPV/Hib immovable)(hereinafter referred to as immovable vaccine immunization vaccine adverse reactions,to explore a more reasonable immune process.Methods 378 healthy infants and young children in the hospital of vaccination,in accordance with the principle of voluntary guardian divided into 2 groups,group A immovable vaccine,group B DTaP and Hib vaccine and IPV,48 h after fol ow-up of 2 groups of infants and young children adverse reactions,and the adverse reaction of two groups were analyzed.Results In A group,B injection site redness incidence rates were 16.5%,10%.Systemic adverse reactions were mainly fever,abnormal crying,lethargy,irritability,loss of appetite,A,B group the incidence of considerable.Conclusion The immovable vaccine adverse reactions similar to conventional single dose of immunization,it simplifies the immunization program,should be recommended.
作者
李娟
LI Juan(The First Affiliated Hospital of Yangtze University,Jingzhou 434000,Hubei,China)
关键词
疫苗
预防接种
不良反应
Vaccine
Vaccination
Adverse reaction
