摘要
目的:探讨和总结原发性甲状旁腺功能亢进症的诊断和治疗方法。方法回顾性总结我院2005年1月~2012年12月收治的56例原发性甲状旁腺功能亢进症的临床资料,包括疾病的临床表现、实验室诊断、影像学诊断、手术治疗、治疗效果。结果56例患者血钙和甲状旁腺素均显著升高,影像学资料均发现甲状旁腺肿物。56例患者成功手术,术后病理有50例为甲状旁腺腺瘤,13例甲状旁腺增生,3例甲状旁腺腺癌,术后无长期甲状旁腺功能减退和喉返神经损伤等并发症。结论原发性甲状旁腺功能亢进症临床表现不典型,高血钙和高甲状旁腺素可作为初步诊断方法,B超联合99mTc-MIBI必要时联合CT或MRI可做出定位诊断,外科手术是治疗原发性甲状旁腺功能亢进症唯一有效的方法。
Objective To summarize and investigate the diagnosis and treatment of primary hyperparathyroidism(PHPT).Methods The clinical data of 56 patients with PHPT who were treated in The First Af iliated Hospital of Guangxi Medial University from January 2003 to December 2011 were retrospectively analyzed.Including Clinical manifestations、Laboratory diagnosis,Imaging diagnosis,Surgical treatment,Therapeutic ef ect.Results In 56 patients,Serum calcium and parathyroid hormone(PTH)Significantly increased,Imaging data were found in all parathyroid tumor.Tumorectomy was performed on 56 patients,50 cases of parathyroid adenoma,13 cases of parathyroid hyperplasia,3 cases of parathyroid carcinoma,no patients have permanent hypoparathyroidism or recurrent nerve injuryand other complication.Conclusion PHPT with atypical clinical manifestations,Serum calcium and PTH assays are the methods of preliminary diagnosis.Doppler ultrasound and 99mTc-MIBI are location diagnosis examination methods.Parathyroidectomy is an ef ective approach to PHPT patients.
作者
张小彬
陆云飞
ZHANG Xiao-bin(The First Affiliated Hospital of Guangxi Medial University,Nanning 530021,Guangxi,China)
