摘要
目的 分析妊娠合并HIV感染母婴阻断及妊娠结局的研究.方法 回顾收集2015年6月1日-2017年12月31日某院住院分娩的HIV感染孕产妇共61例,按照临床救治顺序及情况分为:A组孕前或孕早期即确诊HIV感染并在孕产期采取正规阻断;B组临产前或临产时诊断HIV感染或临产时临时进行药物阻断,2组进行分析.结果 2组在年龄、产次、孕周、感染途径均差异不显著,入选61例全为活产数,其中早产8例,足月低体重5例,A组33例、B组28例全部存活,2组之间新生儿存活上差异不显著无统计学意义,2组在早产、新生儿体重、新生儿Apgar评分差异显著有统计学意义.跟踪随访18个月,平均随访时间12.21±0.23个月,A组婴儿感染1例.A组产妇死亡1例,年龄37岁,其婴儿18个月最后确诊感染.B组婴儿死亡1例,产妇死亡1例.其余新生儿均未感染.结论 在妊娠合并HIV感染孕产妇尽早发现感染、尽早治疗,联合多种阻断措施,最大限度降低HIV母婴传播的可能性,可提高母婴生存质量.
Objective To conduct ananalysis of maternal and child occlusion and pregnancy outcome in pregnant women with HIV infection.Methods From June 1st,2015 to December 31st,2017,the HIV-infected pregnant women who were delivered in a hospital,a total of 61 patients were admitted to the hospital according to the order and conditions of clinical treatment:1.HIV infection was diagnosed before pregnancy or early pregnancy.Regular blockage during pregnancy and childbirth,group A;2,pre-laborary or at labor,diagnosis of HIV infection or temporary medication at the time of labor,group B,two groups for analysis.Results There was no significant difference in age,delivery,gestational age and route of infection between the two groups.61 cases were selected as live births,including 8 cases of premature delivery,5 cases of full-term low body weight,33 cases of group A and 28 cases of group B.there was no significant difference in neonatal survival between the two groups.There was significant difference in Apgar score of neonates.The follow-up period was 18 months with an average follow-up time of(12.21±0.23)months.In group A,1 case of infant infection was found.1 case(37 years old)died in group A,with an average follow-up time of(12.21±0.23)months.The final diagnosis of infection was 18 months.There was 1 infant death in group B and 1 maternal death in group B.The rest of the newborns were not infected.Conclusions It was best to detect infections and treat them as soon as possible in pregnancy with HIV-infected pregnant women,and combine multiple blocking measures to minimize the possibility of mother-to-child transmission of HIV and improve the quality of maternal and child survival.
作者
董完秀
桂华
俸元秀
Dong Wanxiu;Gui Hua;Feng Yuanxiu(Department of Obstetrics,Guilin Maternal and Child Health Hospital,Guilin 541001,Guangxi Zhuang Autonomous Region,China)
出处
《中国病案》
2019年第9期98-101,共4页
Chinese Medical Record
基金
桂林市科学研究与技术开发计划项目(20140120-10)
关键词
妊娠
妊娠合并HIV感染
母婴阻断
妊娠结局
Pregnancy
Pregnancy with HIV infection
Mother and child block
Pregnancy outcome
