摘要
目的 了解三门县女性宫颈高危型人乳头瘤病毒(HPV)感染的特征分布情况,为宫颈癌预防措施和诊断治疗提供科学依据.方法 收集2017年6月至11月行宫颈癌筛查的10200例女性患者资料,分为三个年龄组(35~45岁,46~55岁,56~64岁),对宫颈分泌物采用PCR技术检测15种高危型HPV的基因型别,结合TCT、阴道镜和病理活检结果进行统计学分析.结果 高危型HPV阳性检出率为9.87%,其中单一感染占9.42%,混合感染占4.79%,以58亚型最为常见;高危型HPV总感染率及单一感染率随年龄增加明显升高,宫颈活检阳性检出率以16型、18型及31型较高,差异有统计学意义(P<0.05).结论 根据三门县女性宫颈高危型HPV的感染特征,认真做好女性健康教育,定期进行HPV感染筛查,针对易感人群进行免疫接种,是预防宫颈癌的必要措施.
Objective To investigate the distribution of high-risk HPV infection of cervix uteri in SanmenXian and provide scientific basis for effective preventive intervention and treatment of cervical cancer.Methods 10200 women who had cervical cancer were chose and screened from June 19,2017 to November 24,2017 in People’s Hospital of SanmenXian as research objects,then were divided into three groups(35~45years,46~55years,and 56~64years).Cervical cell specimens and 15 high-risk HPV genotypes were detected by PCR.The results combined of TCT,colposcopy and pathological biopsy were analyzed statistically.Results The total infection rate of high risk type HPV was 9.87%,single infection accounted for 9.42%,mixed infection was 4.79%.The total infection rate and single infection rate increased with the of age.The most common subtybe was 58,but the positive rate of cervical biopsy was highest in type 16,followed type 18 and 31,and the difference was statistically significant(P<0.05).Conclusion According to the characteristics of high-risk HPV infection in female cervix in SanmenXian,it is necessary to do a good job of health education for women,regularly screen for HPV infection and immunize susceptible groups to prevent cervical cancer.
出处
《浙江临床医学》
2019年第1期118-119,共2页
Zhejiang Clinical Medical Journal
关键词
人乳头瘤病毒
高危型
宫颈癌筛查
Human papillomavirus
High-risk type
Cervical cancer screening
