摘要
目的探究丙酸氟替卡松联合特布他林治疗慢性阻塞性肺疾病(COPD)的效果.方法选取2020年4月—2022年4月我院收治的68例COPD患者,采用随机数字表法分为两组.对照组34例采用特布他林治疗,观察组34例采用丙酸氟替卡松联合特布他林治疗.比较两组患者的临床疗效、肺功能指标、血气指标及不良反应发生情况.结果观察组的临床总有效率为97.06%,高于对照组的78.79%,差异有统计学意义(P<0.05).观察组治疗后的各项肺功能指标水平均高于对照组,组间差异有统计学意义(P<0.05).观察组治疗后的血氧饱和度、血氧分压水平均高于对照组,动脉二氧化碳分压低于对照组,组间差异有统计学意义(P<0.05).观察组的不良反应发生率为5.88%,与对照组的2.94%比较,差异无统计学意义(P>0.05).结论丙酸氟替卡松联合特布他林治疗COPD可提高临床疗效,改善患者肺功能和血气指标,不良反应发生率低,值得临床推广使用.
Objective To investigate the effect of fluticasone propionate combined with terbutaline on chronic obstructive pulmonary disease(COPD).Methods A total of 68 COPD patients admitted to our hospital from April 2020 to April 2022 were selected and were divided into two groups by random number table method.34 cases in the control group were treated with terbutaline,and 34 cases in the observation group were treated with fluticasone propionate combined with terbutaline.The clinical efficacy,pulmonary function indexes,blood gas indexes and the incidence of adverse reactions were compared between the two groups.Results The total clinical effective rate of the observation group was 97.06%,which was higher than 78.79%of the control group,and the difference was statistically significant(P<0.05).After treatment,the levels of pulmonary function indexes in the observation group were higher than those in the control group,and the differences between the groups were statistically significant(P<0.05).After treatment,the blood oxygen saturation and partial pressure of oxygen in the observation group were higher than those in the control group,and the arterial carbon dioxide was lower than that in the control group,and the differences between the groups were statistically significant(P<0.05).The incidence of adverse reactions in the observation group was 5.88%,compared with 2.94%in the control group,there was not statistically significant(P>0.05).Conclusion Fluticasone propionate combined with terbutaline in the treatment of COPD can improve the clinical efficacy,pulmonary function and blood gas indexes,and the incidence of adverse reactions is low,which is worthy of clinical application.
作者
张道德
ZHANG Daode(Department of Internal Medicine,Heze Mudan District Psychiatric Hospital,Heze Shandong,274000,China)
出处
《反射疗法与康复医学》
2022年第18期108-111,共4页
Reflexology And Rehabilitation Medicine
关键词
慢性阻塞性肺疾病
丙酸氟替卡松
特布他林
肺功能
血气指标
Chronic obstructive pulmonary disease
Fluticasone propionate
Terbutaline
Pulmonary function
Blood gas indexes
