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TNF-α-238G/A基因多态性与腹主动脉瘤的关联性 被引量:1

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摘要 目的探讨肿瘤坏死因子-α(TNF-α)基因-238位点基因单核苷酸多态性与腹主动脉瘤(AAA)的关联性.方珐选取AAA患者122例,设为观察组,并选取同期健康体检人群100例,设为对照组.PCR技术检测TNF-α基因-238位点基因单核苷酸多态性.结果观察组TNF-α-238G/A基因型中GG基因型频率及G等位基因频率高于对照组(P<0.01).结论TNF-α-238G/A基因多态性与AAA有关联性.
出处 《山东大学学报(医学版)》 CAS 北大核心 2014年第S02期5-6,共2页 Journal of Shandong University:Health Sciences
基金 国家自然科学基金(81060028) 广西自然科学基金资助项目(2011gxnfa018287) 广西中医药民族医药资助项目(GZZC13-21,GZZC13-23) 百色市科技局基金资助项目(百科计20130402,20130403)
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