摘要
采用紫外分光光度法,以纯化水为溶剂,在检测波长为258 nm的条件下,得到标准曲线回归方程为A=0.05033*c+0.05057,R2=0.9998。按照《中国药典》2020版要求,建立磷酸伯氨喹硬胶囊的含量均匀度检查方法,测得磷酸伯氨喹的平均含量为14.25 mg/粒,含量均匀度符合药典标准。
Using ultraviolet spectrophotometry method,purified water as solvent,at 258 nm as detection wavelength,the standard curve regression equation was found as A=0.05033*c+0.05057,R2=0.9998.According to the requirement of 2020 edition of Chinese Pharmacopoeia,the content uniformity of primary aminoquine phosphate capsules was established.The average content of primary aminoquine phosphate was 14.25 mg/capsule,and the content uniformity was in accordance with the Chinese Pharmacopoeia standard.
作者
李想
邓乾华
冯婷婷
张雪华
夏艳
陈荣彬
廖友林
陶桂英
王晓楠
苟文琼
杨善彬
李荣
Li Xiang;Deng Qianhua;Feng Tingting;Zhang Xuehua;Xia Yan;Chen Rongbin;Liao Youlin;Tao Guiying;Wang Xiaonan;Gou Wenqiong;Yang Shanbin;Li Rong(College of Chemistry Chongqing Normal University,Chongqing 401331;Engineering Research Center for Biotechnology of Active Substances,Chongqing 401331,China)
出处
《广东化工》
CAS
2021年第1期162-163,共2页
Guangdong Chemical Industry
基金
重庆市高校创新团队项目(CXTDX201601018)
活性物质生物技术教育部工程研究中心开放基金项目(No.20150408,AS201903)
重庆师范大学成果转化项目基金(15XZH08)
重庆师范大学博士启动项目(12XLB006)
重庆市大学生创新创业训练计划项目(S201910637014,S202010637012)
重庆市社会事业与民生保障科技创新专项项目(cstc2015shmszx80060)