摘要
目的观察腔镜胆囊切除术(Laparoscopic cholecystectomy,LC)与小切口胆囊切除术(Minilaparotomy cholecystectomy,MC)对胆囊炎的治疗效果与安全性。方法选取我院84例胆囊炎患者予以回顾性分析,按照手术方式分为LC组(n=40)与MC组(n=44),比较2组手术前后炎性因子[C反应蛋白(C-reactiveprotein,CRP)、肿瘤坏死因子α(Tumor Necrosis Factor-α,TNF-α)、白介素6(interleukin 6,IL-6)]水平,并观察2组手术指标、术后视觉模拟疼痛(Visual Analogue Scale,VAS)评分、下床活动时间、肛门排气时间与住院时间、术后并发症发生率。结果2组术后CRP、TNF-α、IL-6水平均较术前明显升高(P<0.05),且LC组低于MC组(P<0.05);LC组术中出血量明显少于MC组(P<0.05),手术时间与切口长明显短于MC组(P<0.05);LC组术后VAS评分明显低于MC组(P<0.05),下床活动时间、肛门排气时间与住院时间明显短于MC组(P<0.05);LC组术后并发症总发生率显著低于MC组(P<0.05)。结论相较于MC,LC对机体炎症反应造成的影响较小,手术风险更低,患者术后恢复更快,且术后并发症少,安全性更高。
Objective To observe curative effect and safety of laparoscopic cholecystectomy(LC)and minilaparotomy cholecystectomy(MC)on cholecystitis.Methods A total of 84 cholecystitis patients in the hospital were enrolled for retrospective analysis.According to different surgical methods,they were divided into LC group(n=40)and MC group(n=44).The levels of inflammatory factors[C-reactive protein(CRP),tumor necrosis factor-α(TNF-α),interleukin 6(IL-6)]before and after surgery were compared between the two groups.The surgical indexes,scores of Visual Analogue Scale(VAS),leaving bed time,anal exhaust time,hospitalization time and incidence of postoperative complications in both groups were observed.Results After surgery,levels of CRP,TNF-α,and IL-6 in both groups were significantly increased(P<0.05),which were lower in LC group than MC group(P<0.05).The intraoperative blood loss in LC group was significantly less than that in MC group(P<0.05),operation time and incision length were significantly shorter than those in MC group(P<0.05).The postoperative VAS score in LC group was significantly lower than that in MC group(P<0.05),leaving bed time,anal exhaust time and hospitalization time were significantly shorter than those in MC group(P<0.05).The total incidence of postoperative complications in LC group was significantly lower than that in MC group(P<0.05).Conclusion Compared with MC,effects of LC are fewer on inflammatory response in the body,with lower surgical risk,faster postoperative recovery,fewer postoperative complications and higher safety.
作者
符婷
李力
李玲
FU Ting;LI Li;LI Ling(Department of General Surgery,Chengdu University of Traditional Chinese Medicine,Chengdu 610000,China)
出处
《肝胆外科杂志》
2020年第4期278-281,共4页
Journal of Hepatobiliary Surgery
关键词
胆囊炎
腔镜胆囊切除术
小切口胆囊切除术
安全性
cholecystitis
laparoscopic cholecystectomy
minilaparotomy cholecystectomy
safety
