摘要
帕拉米韦是对甲型和乙型都有效的一种新型抗流感病毒药物,在临床上大多用于治疗季节性普通流感病毒和HxNy型病毒,治疗效果要优于其他抗流感病毒药物。我国上市的帕拉米韦主要有两种用药方式即为口服用药和注射用药,帕拉米韦氯化钠注射液的研发成功使我国率先实现静脉给药,为患者提供了新的治疗途径,本文综述了帕拉米韦的一些相关信息、合成方法和临床应用,为未来抗流感病毒新药的研发提供文献参考。
Peramivir is a new type of anti-influenza drug,which is effective for both type A and Bin clinic,it is mostly used to treat seasonal common influenza virus and HxNy virus,and the therapeutic effect is better than other anti-influenza drugs.There are two main ways to use peramivir on the market in china,oral medicine and injection medicine.The success of the research and development of peramivir sodium chloride injection makes our country take the lead in the realization of intravenous drug delivery,which provides a new way of treatment for patients.This reviewdescribes some related information,synthesis methods and clinical application of peramivir,which provides literature reference for the research and development of new anti-influenza drugs in the future.
作者
彭琳琳
徐志
Peng Lin-lin;Xu Zhi(Huanghuai University,Zhumadian 463000)
出处
《国外医药（抗生素分册）》
CAS
2020年第5期354-360,共7页
World Notes on Antibiotics
基金
河南省高等学校重点科研项目,立项编号:XKPY-2019007
关键词
帕拉米韦
合成
临床
应用
peramivir
synthesis
clinical
application
