摘要
目的探讨薄层螺旋CT诊断以贴壁生长方式为主的T1a或T1b期肺腺癌亚型的价值。方法回顾性分析南召县人民医院2018年11月至2021年12月经手术或穿刺病理证实的T1a或T1b期肺腺癌患者55例,共57个结节。根据病理类型分为贴壁生长为主型组31个及浸润型组26个。分析病变的CT征象、CT值、病变实性成分的面积比及体积比。结果贴壁生长为主型组病变以纯磨玻璃结节及混合磨玻璃结节为主(t=12.435,P=0.002),形态以圆形及椭圆形为主(t=6.167,P=0.046),空泡征发生率低、瘤-肺界面清的比例高(t=11.096、15.731,P=0.001、0.001)。与浸润型组比较,贴壁生长为主型组结节的CT值、结节实性成分的面积比及体积比明显低,差异有统计学意义(χ^(2)=-3.329,-4.471,-2.765,P=0.002,0.001,0.008);结节实性成分的面积比曲线下面积(AUC=0.811)高于体积比曲线下面积(AUC=0.742)。结论薄层螺旋CT的定量及定性分析能够鉴别诊断贴壁生长为主型的T1a或T1b期肺腺癌亚型。
Objective To investigate the diagnostic value of thin slice spiral CT in adherent lung adenocarcinoma with T1a or T1b stage.Methods Fifty-five patients with stage T1a or T1b lung adenocarcinoma including 57 nodules and confirmed by surgical or biopsy pathology in the People’s Hospital of Nanzhao were retrospectively analyzed from November 2018 to December 2021.According to the pathological types of lung adenocarcinoma,the 57 nodules were divided into the adherent growth dominant group(n=31)and the infiltrating group(n=26).The indexes of the CT signs,CT values,area ratio and volume ratio of solid components were analyzed.Results The types of nodules in the adherent growth dominant group were mainly pure ground glass nodules and mixed ground glass nodules(t=12.435,P=0.002),and the shapes were mainly round and oval(t=6.167,P=0.046).The incidence of vacuolar sign in adherent growth dominant group was low,and the proportion of tumor-to-lung interface clearing was high(t=11.096,15.731,P=0.001,0.001).Compared with the infiltrating group,the CT value of nodules and the area ratio and volume ratio of the solid components and the nodules in the adherent growth group were significantly lower,the differences were significant(χ^(2)=-3.329,-4.471,-2.765,P=0.002,0.000,0.008).The area ratio of nodular solid components under the curve(AUC=0.811)was higher than the volume ratio under the curve(AUC=0.742).Conclusions Quantitative and qualitative analysis of thin slice spiral CT can differentiate adherent growth dominated lung adenocarcinoma of T1a or T1b stage.
作者
蒋琢
马庆龙
孟庆成
Jiang Zhuo;Ma Qinglong;Meng Qingcheng(Department of Medical Image,the People’s Hospital of Nanzhao,Nanzhao 474650,China;Department of Medical Image,the Affiliated Tuomor Hospital of Zhengzhou University,Zhengzhou 450008,China)
出处
《临床医学》
CAS
2023年第2期78-81,共4页
Clinical Medicine
基金
河南省科技攻关项目(212102310744)
河南省省部共建重点项目(SBGJ202102057)
关键词
贴壁生长型肺腺癌
X线
体层摄影术
Adherent growth dominated lung adenocarcinoma
X-ray
Tomography
