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新型冠状病毒患者口咽拭子与鼻咽拭子病毒核酸检测阳性率比较 被引量:5

Comparative analysis of the positive rate of nucleic acid detection in COVID-19 patients with oropharyngeal swabs and nasopharyngeal swabs
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摘要 目的:比较新型冠状病毒肺炎患者口咽拭子与鼻咽拭子病毒核酸检测阳性率,为临床提高检测阳性率提供理论依据。方法:随机纳入武汉某医院已确诊的新型冠状病毒住院患者100人,每人均进行口咽拭子核酸检测和鼻咽拭子病毒核酸检测。所有采集咽试纸工作都由医生完成,都统一受过专业采集咽拭子培训。所有病人均在早晨进行采集,采集前不进食进水,不漱口。结果:口咽拭子阳性率为12%,鼻咽拭子阳性率为28%,鼻咽拭子核酸检测阳性率明显高于口咽拭子核酸检测。结论:对于新型冠状病毒肺炎患者,鼻咽拭子核酸检测的诊断阳性率优于口咽拭子。在日常操作中,我们应该尽可能的采用鼻咽拭子检测方法。 Objective The positive rate of nucleic acid detection in oropharyngeal swabs and nasopharyngeal swabs in COVID-19 patients was compared.It provides theoretical basis for improving the positive rate of detection in clinic.Methods 100 hospitalized patients with novel coronavirus confirmed in a hospital in wuhan were randomly?enrolled,and each patient underwent oropharyngeal swab nucleic acid detection and nasopharyngeal swab nucleic acid detection..All pharyngeal test paper collection work is completed by the doctor,all received professional pharyngeal swab collection training.All patients were collected in the morning.Before collection,they did not eat water or gargle.Results The positive rate of oropharyngeal swab was 12%,and that of nasopharyngeal swab was 28%.The positive rate of nasopharyngeal swab was significantly higher than that of oropharyngeal swab,and the difference was statistically significant.Conclusions For COVID-19 patients,the diagnostic positive rate of nucleic acid detection in nasopharyngeal swabs was better than that of oropharyngeal swabs.Nasopharyngeal swabs should be used whenever possible during routine operations.
作者 朱一枫 王湘川 王婧芸 程相洋 刘思言 Zhu Yi-feng;Wang Xiang-chuan;Wang Jing-yun;Cheng Xiang-yang;Liu Si-yan(The Second Affiliated Hospital of Hunan Normal University,The 921st Hospital of the People’s Liberation Army,Changsha 410003,China)
出处 《湖南师范大学学报(医学版)》 2020年第5期57-60,共4页 Journal of Hunan Normal University(Medical Sciences)
关键词 新型冠状病毒肺炎 口腔咽拭子 鼻腔咽拭子 核酸检测 COVID-19 oropharyngeal swabs nasopharyngeal swabs nucleic acid detection
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