摘要
目的探讨脑苷肌肽注射液联合吞咽功能治疗仪治疗卒中后吞咽功能障碍的效果。方法选取2019年7月~2020年7月本院收治的156例卒中后吞咽功能障碍患者,依照随机数表法分为研究组(n=78)和对照组(n=78),对照组采用吞咽功能治疗仪治疗,研究组给予脑苷肌肽注射液联合吞咽功能治疗仪治疗。比较2组患者洼田饮水试验和视频吞咽造影检查(video fluoroscopic swallowing study,VFSS)结果改善情况,食管上括约肌完全开放率、咽期通过时间、卒中相关性肺炎发生率,心理状况评分及不良反应发生率。结果治疗后,研究组洼田饮水试验分级优于对照组(P<0.05),2组VFSS评分较治疗前均升高(P<0.05),且研究组VFSS评分高于对照组(P<0.05);研究组总有效率高于对照组(P<0.05);治疗后,研究组食管上括约肌完全开放率高于对照组(P<0.05),研究组咽期通过时间、卒中相关性肺炎发生率均低于对照组(P<0.05);治疗后,2组心理状况评分较治疗前均降低(P<0.05),且研究组心理状况评分低于对照组(P<0.05);2组不良反应发生率比较,差异无统计学意义(P>0.05)。结论脑苷肌肽注射液联合吞咽功能治疗仪用于治疗卒中后吞咽功能障碍患者能改善临床症状,疗效确切,同时可以降低卒中相关性肺炎发生率,改善心理状况,安全可靠。
Objective To explore the effect of cattle encephalon glycoside and ignotin injection combined with swallowing function therapeutic instrument on swallowing dysfunction after stroke.Methods A total of 156 patients with dysphagia after stroke admitted to our hospital from July 2019 to July 2020 were selected and randomly divided into the study group(n=78)and the control group(n=78).The control group was treated with swallowing function therapeutic instrument,and the study group was treated with cattle encephalon glycoside and ignotin injection comined with swallowing function therapeutic instrument.The improvement of Wata drinking water test and video fluoroscopic swallowing study(VFSS)results,the rate of complete opening of upper esophageal sphincter,the passage time of pharyngeal phase,the incidence of stroke related pneumonia,the score of psychological status,and the incidence of adverse reactions were compared between the two groups.Results After treatment,the grade of Wata drinking water in the study group was better than that in the control group(P<0.05).The VFSS score in both groups was higher than that before treatment(P<0.05),and the VFSS score in the study group was higher than that in the control group(P<0.05).The total effective rate of the study group was higher than that of the control group(P<0.05).After treatment,the rate of complete opening of upper esophageal sphincter in the study group was higher than that in the control group(P<0.05),the pharyngeal passage time and the incidence of stroke associated pneumonia in the study group were lower than those in the control group(P<0.05).After treatment,the scores of psychological status in both groups were lower than those before treatment(P<0.05),and the scores of psychological status in the study group were lower than those in the control group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The combination of cattle encephalon glycoside and ignotin injection with swallowing f
作者
洪湘隆
张慧君
陈少虹
HONG Xiang-long;ZHANG Hui-jun;CHEN Shao-hong(Department of Neurology,Shantou Chaoyang Dafeng Hospital,Shantou 515154,China;Department of Endocrinology,Shantou Chaoyang Dafeng Hospital,Shantou 515154,China;Department of Surgery,Shantou Chaoyang Dafeng Hospital,Shantou 515154,China)
出处
《哈尔滨医科大学学报》
CAS
2023年第4期422-425,461,共5页
Journal of Harbin Medical University
基金
广东省自然科学基金资助项目(2020A0505140006)
汕头市科技计划医疗卫生类别项目(201116196493573)
关键词
脑苷肌肽注射液
吞咽功能治疗仪
卒中
吞咽功能障碍
cattle encephalon glycoside and ignotin injection
swallowing function therapeutic instrument
stroke
dysphagia
