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急性脑梗死脑微出血的影响因素及患者再发心脑血管事件发生率的探讨 被引量:1

Analysis of influencing factors of cerebral microbleeds in patients with acute cerebral infarction and incidence of recurrent cardiovascular and cerebrovascular events
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摘要 目的探讨急性脑梗死(ACI)患者微量脑出血(CMBS)的影响因素及CMBS对ACI患者反复发生心脑血管事件的影响。方法2019年3月至2021年4月,选择在天津港口医院内科住院的200例ACI患者,分为CMBS组(100例)和无CMBS组(100例)。根据两组患者的吸烟、饮酒、糖尿病、高血压和脑出血史,解决了ACI患者CMBS的危险因素,并分析了CMBS对两组患者心血管系统和脑血管事件的影响。结果脑卒中既往史和出血史是CMBS患者最危险的因素之一;年龄、性别、抽烟、高血压和冠状动脉粥样硬化性心脏病(此处称为冠心病)等这些数据不是CMBS的危险因素。在200例患者中,100例为CMBS,检测到100例脑微出血;重度30例,中度20例,轻度50例。主要心脑血管事件是复发性中风、脑卒中、脑出血、缺血性心脏病和死亡,CMBS组与非CMBS组复发性脑卒中和脑出血的发生率差异有统计学意义(P<0.05);CMBS组与非CMBS组在脑梗死、缺血性心脏病和死亡率方面没有明显性差别(P>0.05);CMBS严重程度与卒中复发率之间有很明显的差别(P<0.05);CMBS与脑梗死、脑出血、心脑血管和死亡率之间没有明显性差异(P>0.05)。结论CMBS是脑微血管疾病的特征之一;这是急性缺血性脑梗死患者内出血复发的危险因素之一;既往脑梗死史和脑出血史是脑内微出血的危险因素,脑内出血也可能在一定程度上增加患者心脏病和心脑血管事件的反复发生率,脑内微出血的严重程度与脑内出血的发生率呈正相关;CMBS对于长期服用阿司匹林或抗凝剂的中风患者有很大的影响。 Objective To study the influencing factors of microcerebral hemorrhage(CMBS)in patients with acute cerebral infarction(ACI)and the influence of CMBS on recurrent cardiovascular and cerebrovascular events in patients with ACI.Methods From March 2019 to April 2021,choose to The 200 ACI patients hospitalized in the Department of Neurology of Tianjin Port hospital were divided into a CMBS group(100 cases)and a CMBS-free group(100 cases).According to the history of smoking,drinking,diabetes,hypertension and cerebral hemorrhage of the two groups of patients,the risk factors of CMBS in ACI patients were solved,and the influence of CMBS on the cardiovascular system and cerebrovascular events of the two groups of patients was analyzed.Results Past history of stroke and bleeding history was one of the most risk factors for patients with CMBS;Age,gender,smoking,high blood pressure and coronary atherosclerotic heart disease were not the risk factors of CMBS.Among the 200 patients,100 were CMBS,and 100 cases of cerebral microhemorrhage were detected;30 cases were severe,20 cases were moderate,and 50 cases were mild.The main cardiovascular and cerebrovascular events were recurrent stroke,stroke,cerebral hemorrhage,ischemic heart disease and death.There was significant difference in the incidence of recurrent stroke and cerebral hemorrhage between the CMBS group and the non-CMBS group(P<0.05);There was no significant difference between the CMBS group and the non-CMBS group in terms of cerebral infarction,ischemic heart disease and mortality(P>0.05);There was significant difference between the severity of CMBS and the recurrence rate of stroke(P<0.05);CMBS There was no significant difference with cerebral infarction,cerebral hemorrhage,cardiovascular and cerebrovascular and mortality(P>0.05).Conclusion CMBS is one of the characteristics of cerebral microvascular disease;Tt is one of the risk factors for recurrence of internal hemorrhage in patients with acute ischemic cerebral infarction;Past history of cerebral infarction and c
作者 李靖 LI Jing(Department of Neurology of Tianjin Port Hospital,Tianjin 300456,China)
出处 《医药论坛杂志》 2021年第21期48-52,共5页 Journal of Medical Forum
关键词 脑梗死 脑出血 心脑血管 影响因素 发生率 Cerebral infarction Cerebral ischemia Cardiovascular and cerebrovascular diseases Influencing factors Incidence rate
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