摘要
PLLA-magnesium composites have been widely investigated as potential biodegradable materials for bone implants.Lower/higher corrosion resistance of the crystalized/amorphous magnesium alloys allows tailoring of biodegradability rate.In this work,the amorphous Mg_(65)Zn_(30)Ca_(5)was investigated versus traditional crystalized Mg_(65)Zn_(30)Ca_(5),and a PLLA-Mg_(65)Zn_(30)Ca_(5)composite has been successfully fabricated using hot injection process.Furthermore,the high corrosion resistance of the amorphous Mg_(65)Zn_(30)Ca_(5)prevented the high alkalization and deterioration of mechanical strength.In addition,the high Zn content intended to improve the glass forming ability,also enhances the anti-bacterial property of the PLLA-Mg_(65)Zn_(30)Ca_(5)composite.The remarkable performance of the PLLA-Mg_(65)Zn_(30)Ca_(5)composite shows its promising application in bone repair and tissue regeneration.
基金
supported by National Natural Science Foundation of China(Grant No.51471120)
