摘要
与以往文献报道合成乙酰苯胺方法不同的是:只采用苯胺和冰醋酸为原料,不需要添加任何溶剂或催化剂,在反应釜中加热反应得到乙酰苯胺。实验结果表明:当原料苯胺和冰醋酸的用量摩尔比为1∶2且反应温度为150℃时,在最优的合成条件下,可获得高纯度的乙酰苯胺,产率可达85%。此方法可大大节约乙酰苯胺的合成成本,合成过程更加绿色化。
Unlike the methods reported in previous literatures,acetanilide was synthesized from aniline and glacial acetic acid by heating in a reactor without adding any solvents or catalysts.The molar ratio of the raw aniline and glacial acetic acid is 1:2 and the reaction temperature is 150℃.Under the optimal conditions,the yield of complex may up to 85%with high purity.This method can greatly save the synthesis cost of acetanilide,and the synthesis process is more green.
作者
王淦
Wang Gan(School of Chemistry and Materials Science,Anhui Normal University,Wuhu 241000,China)
出处
《科技通报》
2020年第7期1-3,共3页
Bulletin of Science and Technology
基金
安徽师范大学人才培育项目(2010rcpy042)。
关键词
乙酰苯胺
绿色合成
乙酰化反应
acetaniline
green synthesis
acetylation reaction
